Evidence map›Paper›PMID 42627579›Full record

ArticleAnnals of nuclear medicine2026

Baseline

Yiğithan Okar, Ömer Faruk Şahin, Seval Erhamamcı, Duygu Yörük Atik, Ceren Uğurlu, Elif Kelkit, Rukiye Karabudak, Ayşe Mavi Karakullukçu

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of nuclear medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiğithan OkarDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye. yigithanokar@gmail.com.ORCID http://orcid.org/0009-0002-7005-578X
Ömer Faruk ŞahinDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye.
Seval ErhamamcıDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye.
Duygu Yörük AtikDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye.
Ceren UğurluDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye.
Elif KelkitDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye.
Rukiye KarabudakDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye.
Ayşe Mavi KarakullukçuDepartment of Nuclear Medicine, Umraniye Training and Research Hospital, Elmalikent Adem Yavuz Avenue No:1, 34766, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate whether baseline

methodsThis retrospective single-center study included 48 patients with histopathologically confirmed LARC who underwent baseline

resultsSixteen patients had Ryan 3 poor pathological response and 32 had Ryan 0-2 response. MTV, TLG, HI, and clinical/radiological T stage were significantly higher in Ryan 3 patients, whereas age, sex, CEA, clinical/radiological N stage, SUVmax, and SUVmean did not differ significantly between response groups. SUVmax and SUVmean showed no significant discriminatory value. HI showed the numerically highest AUC (0.760; bootstrapped 95% CI, 0.586-0.899), with predictive performance comparable to MTV (AUC 0.749) and TLG (AUC 0.748). In restricted T-stage-adjusted models, HI, MTV, and TLG remained independently associated with Ryan 3 poor response. Bootstrap optimism-corrected AUCs were 0.847, 0.842, and 0.813 for HI + T stage, MTV + T stage, and TLG + T stage models, respectively.

conclusionBaseline

Indexed as

18F-FDG PET/CTHeterogeneity indexLocally advanced rectal cancerMetabolic tumor volumeNeoadjuvant chemoradiotherapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.