Evidence map›Paper›PMID 42627533›Full record

ArticleSurgical endoscopy2026

Laparoscopic left pancreatectomy is safe for the treatment of pancreatic ductal adenocarcinoma treated by chemoradiotherapy compared to open left pancreatectomy: a single-center retrospective study.

Ana Vlasceanu, Elias Karam, Béatrice Aussilhou, Jeanne Dembinski, Louis de Mestier, Mickaël Lesurtel, Alain Sauvanet, Safi Dokmak

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ana Vlasceanu *Université Paris Cité, Paris, France.
Elias Karam *Université Paris Cité, Paris, France.
Béatrice AussilhouDepartment of HPB Surgery and Liver Transplantation, APHP-Nord, Beaujon Hospital, Département Médico-Universitaire DIGEST, Clichy, France.
Jeanne DembinskiDepartment of HPB Surgery and Liver Transplantation, APHP-Nord, Beaujon Hospital, Département Médico-Universitaire DIGEST, Clichy, France.
Louis de MestierDepartment of Pancreatology and Digestive Oncology - DMU Digest, Beaujon Hospital, Clichy, France.
Mickaël LesurtelUniversité Paris Cité, Paris, France.
Alain SauvanetUniversité Paris Cité, Paris, France.
Safi DokmakUniversité Paris Cité, Paris, France. safi.dokmak@aphp.fr.ORCID http://orcid.org/0000-0002-3335-4388

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeoadjuvant chemoradiotherapy (NACRT) has become a standard in the treatment of borderline and locally advanced pancreatic ductal adenocarcinomas (PDAC). Left pancreatectomy (LP) is the procedure of choice for body and tail PDAC. Only a few data compare the outcomes of laparoscopic and open LP (LLP, OLP) after NACRT.

methodsA monocentric retrospective cohort of patients who underwent LLP or OLP for PDAC after NACRT between 2012 and 2024.

resultsWe included 57 patients, 22 LLP (39%) and 35 OLP (61%) with no difference regarding demographic characteristics. LLP compared to OLP showed less median blood loss (100 vs. 300 mL, p = 0.002), shorter median operative time (210 vs. 255 min, p = 0.003), and median length of stay (8 vs. 14 days, p < 0.001). Rates of Clavien III-IV complications (0 vs. 9%; p = 0.276), mortality (0% vs. 6%, p = 0.518) and grade B/C postoperative pancreatic fistula (0 vs. 3%; p = 1.00) were similar. Median tumor size (25 vs. 21 mm, p = 0.657), median number of harvested lymph nodes (15 vs. 21, p = 0.185), and R0 resection rate (86% for both, p = 1.00) were similar as well. Three-year and five-year overall and disease-free survival were comparable.

conclusionNACRT does not seem to compromise the benefits of laparoscopic surgery as LLP has comparable surgical and oncological outcomes compared to OLP.

Indexed as

ChemoradiotherapyLaparoscopic surgeryLeft pancreatectomyMinimally invasive surgeryNeoadjuvant treatmentPancreatic ductal adenocarcinoma

Identifiers

PMID42627533

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