Evidence map›Paper›PMID 42627009›Full record

ArticleChembiochem : a European journal of chemical biology2026

Chelator Free Radiolabeling and Preclinical Evaluation of η

Qaisar Nadeem, Federica Battistin, Daniel Hernández Valdés, Afaf R Genady, Luis Rafael Silva Mendez, Saman Sadeghi, Olivier Blacque, Roger Alberto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qaisar NadeemInternational Center for Interdisciplinary Research in Sciences, The University of Lahore, Lahore, Pakistan.ORCID https://orcid.org/0000-0002-8034-8933
Federica BattistinDipartimento di Scienze Chimiche e Farmaceutiche, Università di Trieste, Trieste, Italy.ORCID https://orcid.org/0000-0002-6518-9129
Daniel Hernández ValdésDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada.
Afaf R GenadyDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada.
Luis Rafael Silva MendezDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada.
Saman SadeghiDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada.
Olivier BlacqueDepartment of Chemistry, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-9857-4042
Roger AlbertoDepartment of Chemistry, University of Zurich, Zurich, Switzerland.

Funding

Universität Zürich
6 · The paper itself

Abstract

Lenalidomide is a clinically important immunomodulatory drug that exerts activity through binding to the intracellular protein cereblon (CRBN). Despite its widespread therapeutic use, radiolabeling strategies that could enable investigation of lenalidomide pharmacokinetics or support the development of metallodrug analogs have not been reported. We report the synthesis and characterization of sandwich complexes [M(η

Indexed as

Coordination ComplexesLenalidomideRheniumTechnetiumAnimalsHumansMiceStructure-Activity RelationshipTissue DistributionCoordination ComplexesLenalidomideRheniumTechnetiumlenalidomidepharmacomimeticsplanar chiralityrheniumsandwich complexestechnetium

Identifiers

PMID42627009
PMCPMC13495133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.