ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Simulation Study on Preanalytical Variables in Coagulation Testing: Interference Effects and Threshold Determination of Hemolysis, Lipemia, Icterus and Insufficient Sample Volume.
Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectiveTo systematically evaluate the interference degree of hemolysis, lipemia, icterus, and sample collection volume on routine test items of the ACL TOP750 automatic coagulation analyzer, assess the technical performance of the HIL module, verify the manufacturer's anti-interference capability, and establish laboratory-specific anti-interference thresholds for optimizing preanalytical quality management.MethodsGradient interference models of hemolysis, icterus, and lipemia, as well as sample systems with different collection volumes, were constructed. Seven routine coagulation indicators (PT, aPTT, FIB, TT, DD, FDP, AT) were detected, with a relative bias (Bias%) of 10% set as the acceptable standard to comprehensively evaluate the instrument's anti-interference ability.ResultsThe H-index of ACL TOP750 was highly linearly correlated with hemoglobin concentration, the I-index with total bilirubin, and the L-index with triglyceride concentration (R
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.