Evidence map›Paper›PMID 42626766›Full record

SynthesisPhysiotherapy research international : the journal for researchers and clinicians in physical therapy2026

Alterations in Spatiotemporal Parameters in Patients With Lower-Limb Amputation: A Systematic Review With Meta-Analysis.

Luis Augusto Mendes Fontes, Guilherme Auler Brodt, Adna Thalita do Nascimento Silva, Isabela Regina de Lima Andrade, Livia Barboza de Andrade

Abstract readSystematic ReviewMeta-AnalysisReview
In one paragraph

Synthesis in Physiotherapy research international : the journal for researchers and clinicians in physical therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luis Augusto Mendes FontesPostgraduate Program in Integrative Health, Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.ORCID https://orcid.org/0000-0001-7906-0791
Guilherme Auler BrodtBiomechanics, University of Caxias do Sul, Caxias do Sul, Brazil.ORCID https://orcid.org/0000-0002-8094-9835
Adna Thalita do Nascimento SilvaSpecialized Rehabilitation Center, Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.ORCID https://orcid.org/0009-0008-1106-1315
Isabela Regina de Lima AndradeSpecialized Rehabilitation Center, Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.ORCID https://orcid.org/0009-0008-6420-4105
Livia Barboza de AndradePostgraduate Program in Integrative Health, Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.ORCID https://orcid.org/0000-0002-5647-1835

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
6 · The paper itself

Abstract

objectivesTo evaluate differences in spatiotemporal gait parameters in individuals with transfemoral (TFA) and transtibial amputation (TTA) compared with physically able individuals.

methodsThis systematic review with meta-analysis was conducted according to the MOOSE guidelines. Cross-sectional studies or clinical trials that assessed spatiotemporal gait parameters in adults with unilateral TFA or TTA were included. Searches were performed in Medline (via PubMed), CINAHL, Scopus, LILACS, Cochrane Library, and Embase using descriptors related to amputation and gait. Risk of bias was assessed using the Joanna Briggs Institute scale for cross-sectional studies, whereas the meta-analysis was performed using quantitative data for the following outcomes: walking speed, step length, stride length, step width, cadence, stance time, swing time, step time, or stride time.

resultsA total of 12 cross-sectional studies involving 150 individuals with amputation (86 TTA and 64 TFA) and 138 healthy controls were included. Meta-analysis demonstrated a significant reduction in walking speed (mean difference of -0.24; 95% CI -0.32 to -0.17; p < 0.0001; I

conclusionsPatients with lower limb amputation present with functionally compromised gait, characterized by reduced walking speed. Increased step width and reduced stride length are findings that may suggest compensatory strategies during gait and improved balance, which are important requirements for amputee patients. These findings reinforce the need for rehabilitation interventions focused on improving propulsion and postural safety.

trial registrationPROSPERO: CRD42024620098.

Indexed as

Amputation, SurgicalGaitLower ExtremityCross-Sectional StudiesHumansWalking Speedamputeesbalancecadencegaitgait analysis

Identifiers

PMID42626766
PMCPMC13494819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.