ArticleJournal of neurological surgery. Part B, Skull base2026
Single-Barrel versus Double-Barrel Superficial Temporal Artery-to-Middle Cerebral Artery Bypass in Moyamoya Disease: A Systematic Review and Meta-Analysis of Postoperative Stroke Outcomes.
Article in Journal of neurological surgery. Part B, Skull base, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Side-to-Side versus Traditional End-to-Side Approach to STA-MCA Bypass in Moyamoya Disease: A Comparative Meta-analysis.Journal of neurological surgery reports · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Moyamoya disease (MMD) involves progressive stenosis of intracranial arteries and compensatory collateral vessel formation. A novel modification of the single-barrel superficial temporal artery-to-middle cerebral artery (STA-MCA) bypass, the double-barrel bypass, offers increased postoperative flow or draw, although longer operative time. Currently, there is a lack of consensus regarding the impact of the novel double-barrel STA-MCA bypass on the incidence of postoperative stroke for patients undergoing direct extracranial-intracranial bypass for MMD. Methods: We performed a Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA)-compliant systematic review of MEDLINE and Embase from inception through March 2024. A supplemental bibliographic review in Google Scholar was also performed to screen for additional candidate citations. Among 95 candidate citations, 16 underwent full-text review; 5 met the study criteria and were included in a meta-analysis of proportions using random-effects modeling. Results: There was no significant difference in postoperative stroke following single-barrel compared with double-barrel bypass (odds ratio [OR] = 1.28, 95% confidence interval [CI] = 0.26-6.3, Conclusion: Double-barrel STA-MCA bypass does not appear to provide additional postoperative stroke protection or vulnerability compared with the single-barrel; however, given the relatively limited follow-up times, these results may underrepresent long-term benefits. Well-controlled long-term studies are needed to better interrogate the optimal treatment strategies for this vulnerable patient population.
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