Evidence map›Paper›PMID 42626691›Full record

ArticleCase reports in oncology

Deep-Seated Kaposiform Hemangioendothelioma Presenting with Recurrent Hemorrhagic Episodes: A Diagnostic Challenge.

Mária Füssiová, Dominika Dóczyová, Peter Švec, Ján Blatný, Denise M Adams, Peter Rohoň, Monika Grešíková, Zlatica Pavlovičová, Svorad Trnovec, Vlasta Haramiová and 6 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mária FüssiováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Dominika DóczyováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Peter ŠvecBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Ján BlatnýDepartment of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Denise M AdamsComprehensive Vascular Anomalies Program, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA.
Peter RohoňDepartment of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic.
Monika GrešíkováDepartment of Hematology and Transfusiology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Zlatica PavlovičováRadiology Department, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Svorad TrnovecDepartment of Pediatric Neurosurgery, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Vlasta HaramiováPediatric Clinic, Faculty Hospital Nové Zámky, Nové Zámky, Slovakia.
Júlia HorákováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Ivana BoďováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Jaroslava AdamčákováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Tomáš SýkoraBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Miroslava PozdechováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.
Alexandra KolenováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University Bratislava, Bratislava, Slovakia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor frequently complicated by Kasabach-Merritt phenomenon (KMP). Case Presentation: A 21-month-old boy presented with an initial spontaneous scalp hematoma, recurrent hemorrhagic episodes, and progressive consumptive coagulopathy. Imaging revealed an extensive peri- and paravertebral infiltrative mass involving the thoracic and lumbosacral spine, consistent with KHE. Biopsy was deferred because of high bleeding risk. Treatment with sirolimus led to rapid clinical and hematologic remission. At 3.5 years of follow-up, the patient remains free of recurrent KMP with sustained disease control and mild radiological regression. Conclusion: This case highlights the diagnostic challenges of deep-seated KHE and the pivotal role of imaging when biopsy is unsafe.

Indexed as

Diagnostic imagingKaposiform hemangioendotheliomaKasabach-Merritt phenomenonRecurrent hemorrhagic episodesSirolimus

Identifiers

PMID42626691
PMCPMC13493110

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