ArticleFrontiers in nutrition2026
Association between dietary patterns and biological aging among Chinese middle-aged and older adults: evidence from a cross-sectional study.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Previous studies have shown that dietary patterns are associated with health outcomes in Chinese middle-aged and older adults. However, whether dietary patterns are associated with Klemera-Doubal biological age (KDM-BA) and physiological dysregulation (PD) remains unclear. Methods: This cross-sectional study included 4,846 adults aged 45 years and older from the 2009 wave of the China Health and Nutrition Survey (CHNS). Three dietary patterns were derived using principal component analysis based on energy-adjusted food group intakes (g/1,000 kcal): Southern pattern, Western-like pattern, and Plant-rich pattern. KDM-BA acceleration and PD were calculated from routine clinical biomarkers. Linear regression models were used to examine the associations between dietary pattern scores and the two aging measures. Restricted cubic spline regression was applied to evaluate potential non-linear dose-response relationships. Results: The Southern and Western-like patterns were inversely associated with KDM-BA acceleration (β = -0.47, 95% CI: -0.70, -0.24; Conclusions: Dietary patterns were differentially associated with KDM-BA acceleration and PD. These findings suggest that specific dietary patterns are associated with healthy aging in Chinese middle-aged and older adults.
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