Evidence map›Paper›PMID 42626598›Full record

ArticleExtracellular vesicle2026

Mitochondria-containing large extracellular vesicles target mouse motor neurons upon intramuscular injection.

Paromita Paul Pinky, Zhong-Min Wang, Purva Khare, Jhanvi R Jhaveri, Abigail Sullivan, Vivek Basudkar, Krithika S Rao, Audrey Lawrence, Adithri Pingali, Kandarp M Dave and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Extracellular vesicle, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Paromita Paul PinkyGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Zhong-Min WangInternal Medicine, Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Purva KhareGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Jhanvi R JhaveriGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Abigail SullivanGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Vivek BasudkarGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Krithika S RaoPittsburgh Heart Lung Blood Vascular Institute, University of Pittsburgh Medical School, Pittsburgh, PA 15213.
Audrey LawrenceGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Adithri PingaliGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Kandarp M DaveGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Donna B StolzCenter for Biologic Imaging, University of Pittsburgh Medical School, Pittsburgh, PA 15213.
Ming SunCenter for Biologic Imaging, University of Pittsburgh Medical School, Pittsburgh, PA 15213.
Si-Yang ZhengDepartment of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213.
Sruti S ShivaPittsburgh Heart Lung Blood Vascular Institute, University of Pittsburgh Medical School, Pittsburgh, PA 15213.
Carol MilliganDepartment of Translational Neuroscience, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Osvaldo DelbonoInternal Medicine, Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157.
Devika S ManickamDepartment of Neurology, McGovern Medical School, Houston, TX 77030.

Funding

Pain and Neurodegenerative Undergraduate Research Experiences: Interacting with community partners to build specialized and enhanced neurologic disease programs for undergraduates.R25NS100118 · NINDS · DUQUESNE UNIVERSITY · PI MICHAEL CASCIO, David Bruce Heisler · 2018 to 2026
$825k
NINDS NIH HHS R25 NS100118
6 · The paper itself

Abstract

Amyotrophic Lateral Sclerosis (

Indexed as

ALSEVsextracellular vesicleslarge EVsmitochondriamotor neuronssmall EVsspinal cord

Identifiers

PMID42626598
PMCPMC13492514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.