Evidence map›Paper›PMID 42626395›Full record

ArticleACS nano medicine2026

Dual-Action Nucleic Acid Nanoparticles: Innate Immune Activation and Silver Nanocluster-Mediated Targeting of Intracellular Bacteria.

Leyla Danai, Christina J Bayard, Krishna Majithia, Thomas Perrell, Phong Nguyen, Michael G Walter, Alexander Lushnikov, Alexey V Krasnoslobodtsev, M Brittany Johnson, Yaroslava G Yingling and 1 more

Abstract read
In one paragraph

Article in ACS nano medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Leyla DanaiChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.ORCID 0009-0006-7391-8025
Christina J BayardDepartment of Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27695, United States.ORCID 0009-0002-5344-3713
Krishna MajithiaDepartment of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Thomas PerrellChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Phong NguyenChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Michael G WalterChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Alexander LushnikovDepartment of Physics, University of Nebraska Omaha, Omaha, Nebraska 68182, United States.
Alexey V KrasnoslobodtsevDepartment of Physics, University of Nebraska Omaha, Omaha, Nebraska 68182, United States.
M Brittany JohnsonDepartment of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Yaroslava G YinglingDepartment of Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27695, United States.ORCID 0000-0002-8557-9992
Kirill A AfoninChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.ORCID 0000-0002-6917-3183

Funding

SMART NANPs: new molecular platform for communication with human immune system and modulation of therapeutic responsesR35GM139587 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI AFONIN, KIRILL A · 2021 to 2025
$1.8M
NIGMS NIH HHS R35 GM139587
6 · The paper itself

Abstract

Intracellular bacterial infections, such as those caused by

Indexed as

antibacterialNANPsRIG-I activationS. aureusSilver nanoclusters

Identifiers

PMID42626395
PMCPMC13492571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.