ReviewFrontiers in microbiology2026
Advances in gut microbiota research among pediatric patients with sleep-disordered breathing.
Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Sleep-disordered breathing (SDB) in children encompasses a spectrum of disorders characterized by abnormal breathing during sleep, with obstructive sleep apnea (OSA) being the most prevalent phenotype. Traditionally, SDB has been viewed as a disorder involving local upper airway structural and neuromodulatory abnormalities. In recent years, the role of the gut microbiota as the "second brain" and a systemic regulator of immunity and metabolism has gained increasing prominence. Accumulating evidence suggests a bidirectional association between pediatric SDB and gut microbiota dysbiosis. This review summarizes recent advances in research on the interplay between pediatric SDB and the gut microbiota, explores the underlying mechanisms-particularly those governing gut microbiota-mediated cognitive and behavioral alterations-and discusses potential diagnostic biomarkers and novel adjunctive therapeutic strategies targeting the gut microbiota. It aims to provide new perspectives for the comprehensive management of pediatric SDB.
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