ArticleCureus2026
The Effect of Central Venous Catheter Dressings on Preventing Catheter-Related Bloodstream Infections: A Comparative Study of Patients in Intensive Care Post Abdominal Surgery.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimTo evaluate the incidence of catheter-related bloodstream infections and the safety characteristics of chlorhexidine gluconate (CHG)-impregnated transparent dressings compared with standard transparent dressings in patients monitored in the intensive care unit post abdominal surgery.
methodsA total of 102 patients who had a central venous catheter inserted via the internal jugular or subclavian vein and for whom the catheters were expected to remain in place for ≥48 hours were included in the study. Patients with disrupted skin integrity, known allergies to dressing components, or pre-existing bloodstream infections prior to catheterization were excluded. Patients were randomly assigned in a 1:1 ratio to either the CHG-impregnated transparent polyurethane dressing group (n=51) or the standard transparent dressing group (n=51). According to the protocol, dressings were replaced every seven days in the CHG group and every 2-3 days in the standard group, or as clinically necessary. The primary discontinuation was defined as the development of catheter-related bloodstream infections. Categorical variables were analyzed using the chi-square/Fisher test, while independent risk factors were evaluated using logistic regression (p<0.05).
resultsThe groups were similar in terms of age, gender, catheterization duration, and intensive care duration. The catheter-related bloodstream infection rate was 5.9% (3/51) in the CHG group and 25.5% (13/51) in the standard group, and the difference was statistically significant (p=0.014); the absolute risk reduction was 19.6%. Multivariate analysis demonstrated that standard dressing use was an independent and strong risk factor for catheter-related bloodstream infection (OR: 21.2; 95% CI: 2.5-177.1; p=0.005). Each additional day of catheterization increased the risk of infection (OR: 1.2 (1.1-1.3); p=0.002 ), and female gender showed an independent association (OR: 8.1 (1.5-44.6); p=0.016). Skin reactions were found in 5.9% (3/51) of the CHG group and 27.5% (14/51) of the standard dressing group, with a significant difference between the groups (p=0.037). Reaction severity was found to be significantly lower in the CHG group (p=0.045). Major complications and dressing intolerance were observed only in the standard dressing group (3.9%), while no such complications were observed in the CHG group (p=0.010).
conclusionThe routine inclusion of CHG-impregnated transparent dressings in central venous catheter care protocols in intensive care units is considered a powerful strategy that can contribute to reducing the incidence of catheter-related bloodstream infections, improving patient safety, and managing care processes more effectively.
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