ArticleWorld journal of methodology2026
Efficacy of duodenoscope with disposable distal cap in reducing microbial contamination: A systematic review and meta-analysis.
Article in World journal of methodology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent microbial contamination of duodenoscopes remains a critical vector for healthcare-associated infections involving multidrug-resistant organisms. Despite adherence to standard high-level disinfection (HLD) protocols, contamination rates remain alarming. To mitigate this risk, the United States Food and Drug Administration has recommended transitioning to duodenoscopes with disposable components.
aimTo investigate the efficacy of disposable distal cap compared to standard duodenoscope reprocessing with HLD in reducing microbial contamination.
methodsFollowing Preferred Reporting Items for Systematic Reviews and Meta-analysis and Cochrane guidelines, we conducted a systematic search of MEDLINE, EMBASE, Google Scholar, and grey literature for randomized controlled trials comparing disposable distal cap
resultsFour randomized controlled trials met the inclusion criteria, encompassing 1092 duodenoscopes (543 disposable distal cap, 549 standard). The use of disposable cap demonstrated a significant and substantial reduction in post-HLD contamination rates. The pooled analysis showed a risk ratio of 0.32 (95% confidence interval: 0.16-0.67;
conclusionDisposable distal cap significantly decreases microbial contamination rates compared to standard duodenoscope reprocessing protocols. This technology represents a robust and effective strategy to enhance the safety of duodenoscope reprocessing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.