ArticleCureus2026
Cervical Ganglioneuroma in Neurofibromatosis Type 1 Presenting as a Carotid Space Mass With Postoperative Horner Syndrome.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ganglioneuromas are uncommon benign tumours derived from neural crest cells and composed of mature ganglion and Schwannian stromal elements. They most frequently arise in the posterior mediastinum and retroperitoneum, while cervical involvement is rare. Although ganglioneuroma may occur in association with neurofibromatosis type 1, such presentations are infrequently reported. Surgical excision is generally curative; however, postoperative sympathetic dysfunction, including Horner syndrome, may occur because of the close anatomical relationship of these tumours to the cervical sympathetic chain. We report the case of a 24-year-old woman with sporadic neurofibromatosis type 1 who presented with right-sided neck pain and temporomandibular discomfort. Clinical examination revealed a firm, non-tender, non-pulsatile mass in the right anterior cervical triangle, with preserved vocal cord mobility on flexible nasoendoscopy. Magnetic resonance imaging demonstrated a well-circumscribed fusiform lesion within the right carotid space extending from C1 to C6, with anterolateral displacement of the common carotid artery and splaying of the carotid bifurcation, consistent with a neurogenic tumour. Following multidisciplinary discussion, the lesion was excised via a transcervical approach. Histopathological examination confirmed ganglioneuroma with degenerative changes and no malignant features. Postoperatively, the patient developed ipsilateral ptosis and miosis consistent with Horner syndrome. Ophthalmological assessment confirmed sympathetic dysfunction. Her symptoms gradually resolved, with complete recovery by six months. Follow-up magnetic resonance imaging demonstrated no residual or recurrent disease, and serial imaging over four years showed no recurrence and stability of a smaller contralateral lesion. This case highlights cervical ganglioneuroma as a rare differential diagnosis for carotid space masses in patients with neurofibromatosis type 1. Although complete excision offers an excellent prognosis, careful preoperative counselling and operative planning are essential because of the risk of temporary sympathetic chain dysfunction, particularly in lesions extending toward the skull base.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.