ReviewJGH open : an open access journal of gastroenterology and hepatology2026
Nursing-Led Support Across the Standard Care-Clinical Trial-Standard Care Pathway in Inflammatory Bowel Disease: A Review With Realist-Informed Interpretation.
Review in JGH open : an open access journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- IBD Nurse-Led Clinical Pathways to Optimize Patient Safety in Advanced Therapies: A Narrative Review.Digestive diseases and sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: To examine how nursing-led support may influence engagement, continuity, adherence, retention, and protocol enactment across the standard care-clinical trial-standard care pathway in individuals with inflammatory bowel disease (IBD). Methods and Results: This focused narrative review used selected realist-informed interpretive principles as a conceptual lens to synthesize heterogeneous literature related to IBD clinical trials, specialist and clinical research nursing, placebo and nocebo processes, health literacy, teach-back, telemonitoring, continuity of care, transitions, implementation, and intervention fidelity. Rather than conducting a formal realist review, realist concepts were used to inform the interpretation of how contextual factors, participant reasoning, and implementation conditions may influence nursing-led support across the clinical trial pathway. Literature was identified through iterative searches in PubMed/MEDLINE, Scopus, and Google Scholar, complemented by backward and forward citation tracking. Five interrelated supportive functions emerged across the reviewed literature: expectation-shaping during screening and enrolment; literacy-sensitive education and teach-back; structured hybrid contact and continuity support; transition-sensitive assistance during trial entry, amendment, and exit phases; and governance strategies promoting role clarity, safety, and equity. Nursing-led support appeared most relevant when it helped participants interpret uncertainty, understand protocol expectations, maintain continuity, and navigate vulnerable transitions. These functions may contribute to engagement, adherence, retention, and timely symptom reporting by strengthening trust, self-efficacy, relational continuity, and adherence to practical protocols. Conclusion: Nursing-led support may represent a potential mechanism-bearing component of IBD clinical trial participation rather than a purely administrative activity. Transition-sensitive, literacy-aware, and continuity-oriented nursing strategies may support safer, more equitable, and more sustainable engagement across increasingly complex clinical trial pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.