Evidence map›Paper›PMID 42626115›Full record

SynthesisFrontiers in cellular and infection microbiology2026

Global research landscape and emerging trends of respiratory microbiota and asthma: a bibliometric analysis.

Qixin Wang, Yongsheng Yu, Baiwu Liang, Lijun Chen, Hongxia Yu, Xianhui Luo, Xiaochao Du, Mo Liao, Haizong Hu, Mei Yang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qixin WangDepartment of Respiratory and Critical Care Medicine, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Yongsheng YuRehabilitation Center, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Baiwu LiangDepartment of Oncology, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Lijun ChenDepartment of Respiratory and Critical Care Medicine, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Hongxia YuDepartment of Respiratory and Critical Care Medicine, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Xianhui LuoDepartment of Respiratory and Critical Care Medicine, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Xiaochao DuDepartment of Respiratory and Critical Care Medicine, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Mo LiaoRehabilitation Center, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Haizong HuDepartment of Respiratory and Critical Care Medicine, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.
Mei YangDepartment of Respiratory and Critical Care Medicine, Dazhou Integrated Traditional Chinese Medicine &Western Medicine Hospital, Dazhou Second People's Hospital, Dazhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Asthma is a heterogeneous chronic airway disease in which respiratory microbiota is increasingly recognized as key contributors to airway inflammation, immune regulation, and clinical phenotypes. However, the rapid growth of publications has resulted in a fragmented knowledge landscape, hindering the identification of core contributors and emerging research directions. Methods: A bibliometric analysis was conducted using publications from the Web of Science Core Collection (WoSCC) and Scopus (2000-2025). Bibliometrix, VOSviewer, and CiteSpace were applied independently to each database to assess publication trends, collaboration networks, co-citation structures, keyword co-occurrence, and burst dynamics, enabling cross-database validation. Results: A total of 516 WoSCC and 572 Scopus records were included. Both datasets showed consistent growth after 2015, with comparable annual growth rates. The United States, China, and the United Kingdom were leading contributors and central collaboration hubs. Core journals and co-citation patterns were highly concordant across databases. Three reproducible research themes were identified: respiratory microbiota dysbiosis, immune-microbiota interactions, and early-life microbial exposure. Temporal analyses consistently showed a shift toward phenotype-oriented and mechanistic research, with increasing focus on disease severity, immune regulation, and biomarker-related topics. Conclusion: This dual-database bibliometric study provides a validated overview of the evolving research landscape of respiratory microbiota in asthma. The findings suggest a transition toward more integrative and mechanism-oriented research, offering a structured framework to guide future studies and methodological development.

Indexed as

AsthmaBibliometricsMicrobiotaRespiratory SystemDysbiosisHumansasthmabibliometric analysisdysbiosisimmune regulationrespiratory microbiota

Identifiers

PMID42626115
PMCPMC13491430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.