Evidence map›Paper›PMID 42626074›Full record

ArticleHealth science reports2026

Immuno-Informatics Design of Multi-Epitope Vaccine Candidate Against

Samson Anjikwi Malgwi, Sinalo Mani, Iliya Dauda Kwoji, Victoria T Adeleke, Matthew A Adeleke, Moses Okpeku

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samson Anjikwi MalgwiDiscipline of Biological Sciences, School of Agriculture and Sciences University of KwaZulu-Natal Durban South Africa.ORCID https://orcid.org/0000-0002-8827-8191
Sinalo ManiAgricultural Research Council-Animal Production GI Microbiology and Biotechnology Unit Irene Gauteng South Africa.ORCID https://orcid.org/0000-0001-8143-9215
Iliya Dauda KwojiDiscipline of Biological Sciences, School of Agriculture and Sciences University of KwaZulu-Natal Durban South Africa.ORCID https://orcid.org/0000-0003-3454-1190
Victoria T AdelekeDiscipline of Chemical Engineering Mangosuthu University of Technology Durban South Africa.ORCID https://orcid.org/0000-0002-4495-0644
Matthew A AdelekeDiscipline of Biological Sciences, School of Agriculture and Sciences University of KwaZulu-Natal Durban South Africa.ORCID https://orcid.org/0000-0002-3271-8442
Moses OkpekuDiscipline of Biological Sciences, School of Agriculture and Sciences University of KwaZulu-Natal Durban South Africa.ORCID https://orcid.org/0000-0002-8337-6294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Bovine anaplasmosis is an intracellular tick-borne, non-contagious disease caused by gram-negative bacteria of the family Anaplasmataceae and order Rickettsia. Methods: The development and design of a multiepitope vaccine construct targeting the major surface protein-4 (MSP-4) antigen were accomplished using an immunoinformatic approach. Results: The vaccine design incorporated 10 CD8 Conclusion: The vaccine construct induced sufficient humoral and cellular response during immune simulation. Analysis of the immunogen model further confirmed its potential to stimulate the immune system effectively against bovine

Identifiers

PMID42626074
PMCPMC13490860

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.