ArticleACS omega2026
Alkylsuccinylated Bentonite-GelMA Hybrid Hydrogels for Enhanced Mechanics and Osteogenic Drug Delivery.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bentonite is an attractive inorganic material for biomedical applications owing to its biocompatibility and large surface area. Here, we report a straightforward yet effective alkylsuccinylation strategy to tailor the bentonite surface with hydrophobic functionalities. Successful organic modification was confirmed by Fourier transform infrared (FTIR) spectroscopy and thermogravimetric analysis (TGA). The alkylsuccinylated bentonite was incorporated into gelatin methacryloyl (GelMA)-based hydrogels to construct inorganic-organic hybrid systems. In particular, GelMA hydrogels containing octadecylsuccinylated bentonite (O-bent) exhibited 1.3-, 1.7-, and 2.8-fold increases in storage modulus (G') compared to pristine GelMA hydrogels, as measured by rheometry. The GelMA/O-bent composite hydrogels showed no detectable cytotoxicity at O-bent contents of 0.1%. In addition, the hydrophobically modified bentonite exhibited sustained release behavior for hydrophobic molecules, indicating its potential as a drug reservoir. Moreover, the GelMA/O-bent composites effectively adsorbed the hydrophobic osteogenic agent phenamil through a simple adsorption-washing process, achieving a loading efficiency of 65%. Phenamil-loaded GelMA/O-bent hydrogels further demonstrated enhanced osteogenic activity
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.