ArticleFrontiers in oncology2026
Breast implant-associated anaplastic large cell lymphoma: a case report and literature review.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare T-cell non-Hodgkin lymphoma primarily associated with textured breast implants. Its pathological hallmarks include CD30 positivity, ALK negativity, and clonal T-cell receptor gene rearrangement. Complete surgical excision is the primary treatment modality, and early diagnosis combined with standardized management is associated with a favorable prognosis. We report a case of BIA-ALCL in a 47-year-old female who presented with breast swelling 20 years after receiving textured breast implants. To the best of our knowledge, this is the first documented case of BIA-ALCL in mainland China. Preoperative aspiration was not suggestive of BIA-ALCL, and the diagnosis was ultimately confirmed through histopathological examination of the capsule tissue. Based on a comprehensive postoperative systemic evaluation, no adjuvant therapy was required.
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