Evidence map›Paper›PMID 42625621›Full record

ArticleFrontiers in cardiovascular medicine2026

Pre- and intra-operative risk factors for re-operation after valve sparing aortic root replacement using the David technique. Results from two European centers.

Armin Darius Peivandi, Andreas Martens, Felix Fleißner, Ruslan Natanov, Morsi Arar, Florian Helms, Malakh Shrestha, Heike Krüger, Erik Beckmann, Arjang Ruhparwar and 5 more

Abstract read
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In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Armin Darius PeivandiDepartment of Cardiac Surgery, Klinikum Oldenburg, Oldenburg, Germany.
Andreas MartensDepartment of Cardiac Surgery, Klinikum Oldenburg, Oldenburg, Germany.
Felix FleißnerDepartment of Cardiac Surgery, Klinikum Oldenburg, Oldenburg, Germany.
Ruslan NatanovDepartment of Cardiac Surgery, Klinikum Oldenburg, Oldenburg, Germany.
Morsi ArarDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Florian HelmsDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Malakh ShresthaDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Heike KrügerDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Erik BeckmannDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Arjang RuhparwarDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Alessandro LeoneDivision of Cardiac Surgery, Cardiac Surgery Department, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Giacomo MuranaDivision of Cardiac Surgery, Cardiac Surgery Department, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Costanza FiaschiniDivision of Cardiac Surgery, Cardiac Surgery Department, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Davide PaciniDivision of Cardiac Surgery, Cardiac Surgery Department, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Francesco CampaniniDivision of Cardiac Surgery, Cardiac Surgery Department, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study investigates pre- and intra-operative risk factors for re-operation after valve sparing aortic root replacement using the David technique to develop a risk model. Methods: A retrospective cohort study of two European centers, comprising data from 07/1993 to 01/2025 was performed. Follow up time was 120 (IQR: 141) months. Primary outcome was aortic valve re-operation. Prediction model was developed using uni- and multivariable logistic regression analysis. A risk score was derived. Calibration in the large and slope were performed. Receiver operating characteristic (ROC) analysis allowed discrimination assessment. Results: 1,074 patients were included. Male sex (OR: 1.98; 95% CI: 1.16-3.39, Conclusion: Bicuspid aortic valve, higher pre-operative AI, NYHA grade and male sex were independent risk factors for re-operation. Higher age and larger prosthesis sizes were protective factors. Further multi-center research is needed to validate and refine the prediction model.

Indexed as

David operationpredictionre-operationrisk scorevalve sparing root replacement

Identifiers

PMID42625621
PMCPMC13489906

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