Evidence map›Paper›PMID 42625559›Full record

ArticleVeterinary ophthalmology2026

Zygomatic Sialadenitis as a Rare Cause of Exophthalmos in a Dog.

Katrina E V Jones, Manabu Kurihara, Hans D Westermeyer, Danielle Meritet

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In one paragraph

Article in Veterinary ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katrina E V JonesDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0001-9163-214X
Manabu KuriharaDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0009-0008-2009-8232
Hans D WestermeyerDepartment of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0001-8146-068X
Danielle MeritetMolecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0003-4445-7291

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the clinical presentation, diagnostic findings, and surgical management of zygomatic sialadenitis associated with retrobulbar disease in a dog following extensive dental extractions. ANIMALS STUDIED: A 10-year-old spayed female Cavalier King Charles Spaniel. PROCEDURES: The dog was evaluated for acute-onset right-sided exophthalmos that developed after a recent dental procedure involving 15 extractions. Ophthalmic examination identified marked exophthalmos, pain on opening of the mouth, lagophthalmos, and a superficial corneal ulcer. Computed tomography (CT) of the head was performed and revealed a tubular fluid-filled structure likely consistent with a retrobulbar abscess and right-sided zygomatic sialadenitis. Samples for cytology and culture were obtained. Initial medical management included intravenous fluids, broad-spectrum systemic antibiotics, analgesics, topical antibiotics, and ocular antihypertensive medications.

resultsCytology revealed septic suppurative inflammation. Microbial culture identified Bacteroides pyogenes , an anaerobic organism not typically associated with antimicrobial resistance. Histopathology confirmed subacute zygomatic sialadenitis with associated cellulitis. Due to progressive clinical deterioration and vision loss, transpalpebral exenteration with zygomatic sialoadenectomy was performed. Postoperative recovery was uneventful, with complete resolution of periocular swelling and pain on follow-up examination.

conclusionsZygomatic sialadenitis should be considered a differential diagnosis for retrobulbar disease in dogs, particularly when cases are refractory to medical management. In this case, persistent salivary secretions likely contributed to ongoing inflammation and clinical signs. Advanced imaging facilitated accurate diagnosis, and surgical removal of the affected gland was necessary for definitive resolution.

Indexed as

Dog DiseasesExophthalmosSialadenitisZygomaAnimalsDogsFemaleTooth Extraction

Identifiers

PMID42625559
PMCPMC13494686

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.