Evidence map›Paper›PMID 42625474›Full record

ArticleMolecular nutrition & food research2026

Protective Effect of a Heat-Stabilized Bacteria Probiotic Preparation (VSL#3-HS) in a Mouse Model of Ulcerative Colitis Induced by Dextran Sulfate Sodium.

Chiara Santucci, Alessio Torcinaro, Francesca De Santa, Maria Cristina Giustiniani, Diego Mora, Stefania Arioli, Lucrezia Laterza, Georgios Strimpakos, Stefano Farioli-Vecchioli, Carla Petrella

Abstract read
In one paragraph

Article in Molecular nutrition & food research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chiara SantucciInstitute of Biochemistry and Cell Biology, Monterotondo, Italy.
Alessio TorcinaroInstitute of Biochemistry and Cell Biology, Monterotondo, Italy.
Francesca De SantaInstitute of Biochemistry and Cell Biology, Monterotondo, Italy.
Maria Cristina GiustinianiDepartment of Pathology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Diego MoraDepartment of Food, Environmental and Nutritional Sciences, University of Milan, Milan, Italy.
Stefania ArioliDepartment of Food, Environmental and Nutritional Sciences, University of Milan, Milan, Italy.
Lucrezia LaterzaDepartment of Translational Medicine and Surgery, University Cattolica del Sacro Cuore, Rome, Italy.
Georgios StrimpakosInstitute of Biochemistry and Cell Biology, Monterotondo, Italy.
Stefano Farioli-VecchioliInstitute of Biochemistry and Cell Biology, Monterotondo, Italy.
Carla PetrellaInstitute of Biochemistry and Cell Biology, Rome, Italy.

Funding

Beingpharma s.r.l
6 · The paper itself

Abstract

Postbiotics, composed of inanimate microorganisms or their components, are gaining attention for managing intestinal discomfort, being safer than probiotics for vulnerable patients. This study investigates the effects of short-term consumption of a heat-stabilized VSL#3 formulation (VSL#3

Indexed as

Colitis, UlcerativeProbioticsAnimalsColonDextran SulfateDisease Models, AnimalHot TemperatureInterleukin-1betaInterleukin-6MaleMiceMice, Inbred C57BLOccludinTumor Necrosis Factor-alphaDextran SulfateInterleukin-1betaInterleukin-6OccludinTumor Necrosis Factor-alphaantiinflammationexperimental colitisheat stabilizationnonviable probioticsrecovery of clinical signs

Identifiers

PMID42625474
PMCPMC13494568

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.