Observational studyBrain and behavior2026
Physical Activity and Cognitive Function Among Chinese Adults Aged 45 Years and Older with Self-Reported Hearing Loss: A 9-Year Longitudinal Study.
Observational study in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPhysical activity may help prevent dementia in people with hearing loss, but evidence on long-term behavioural heterogeneity is limited. This study examined dose-response associations between physical activity and cognitive impairment and explored heterogeneity in long-term physical activity trajectories and their associations with cognitive function among adults with self-reported hearing loss.
methodsData were from the China Health and Retirement Longitudinal Study (2011-2020), including 2055 adults aged ≥ 45 years with hearing difficulties and normal cognition at baseline. Physical activity, assessed biennially using the International Physical Activity Questionnaire, was expressed as metabolic equivalent minutes per week. Cognitive function in 2020 was measured by validated tests of episodic memory and mental status (range 0-21). Multiple linear regression examined associations between activity trajectories and cognition.
resultsPhysical activity showed an L-shaped relationship with cognitive impairment. Three trajectories were identified: slight decline (70.61%), sharp drop (15.28%), and rise-then-fall (14.11%). Compared with the slight-decline group, the rise-then-fall group had lower global cognition (β = -0.621, 95% CI -1.022--0.219) and mental status scores (β = -0.449, 95% CI -0.648--0.249). This trajectory was more common among men, younger rural residents, frequent drinkers, non-nappers, and those with depressive symptoms.
conclusionsAmong adults with self-reported hearing loss, physical activity showed an L-shaped association with cognitive impairment, and participants following an unstable rise-then-fall activity pattern had lower cognitive function. These findings highlight heterogeneity in physical activity patterns within this population and support the need for strategies that help sustain long-term physical activity engagement.
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