Evidence map›Paper›PMID 42624947›Full record

ArticleScientific reports2026

Jingling Granules alleviate atherosclerosis through activating autophagy and inhibiting human umbilical vein endothelial cells apoptosis.

Yuhan Wang, Yanzi Liu, Dong Niu, Chang Liu, Qiang Wu, Li Cao, Feng Gao, Shu Lu, Fuming Liu

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuhan WangJiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.
Yanzi LiuJiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.
Dong NiuWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, 214071, Jiangsu, China.
Chang LiuWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, 214071, Jiangsu, China.
Qiang WuJiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China.
Li CaoAffiliated Wuxi Fifth Hospital of Jiangnan University, The Fifth People's Hospital of Wuxi, Wuxi, 214000, Jiangsu, China.
Feng GaoWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, 214071, Jiangsu, China. fsyy01106@njucm.edu.cn.
Shu LuWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi Hospital of Traditional Chinese Medicine, Wuxi, 214071, Jiangsu, China. wxzy001@njucm.edu.cn.
Fuming LiuJiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu, China. doctor.liufuming@outlook.com.

Funding

the Key Planning Project for the Science and Technology Development of Traditional Chinese Medicine of Jiangsu Province ZD201906the Six Talent Peaks Project in Jiangsu Province TD-SWYY-069
6 · The paper itself

Abstract

Atherosclerosis (AS) remains a leading cause of cardiovascular morbidity worldwide. Strategies that promote autophagy and limit apoptosis hold therapeutic promise. Jingling Granules (JLG), a clinically used formulation, have shown vascular protective effects, but the underlying mechanisms are incompletely understood. Here, we investigated whether JLG attenuates atherosclerosis by modulating autophagy and apoptosis through mTOR signaling. In high-fat diet-fed ApoE

Indexed as

ApoptosisAtherosclerosisAutophagyDrugs, Chinese HerbalHuman Umbilical Vein Endothelial CellsAnimalsDiet, High-FatHumansMaleMiceSignal TransductionTOR Serine-Threonine KinasesDrugs, Chinese HerbalTOR Serine-Threonine KinasesApoE−/− miceHyperlipemiaMTORTraditional Chinese medicineVascular endothelial damage

Identifiers

PMID42624947
PMCPMC13494044

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.