Evidence map›Paper›PMID 42624944›Full record

ArticleNPJ digital medicine2026

A scoping review on the mental health harms of LLM-based chatbots.

Alexander Diel, John Torous, Pim Cuijpers, Jens Kleesiek, Felix Nensa, Niels Weber, Franziska Faust, Tania Josan Lalgi, Finley Sam Mellis, Martin Teufel and 1 more

Erratum issuedAbstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Alexander DielClinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, University of Duisburg-Essen, Essen, Germany. alexander.diel@lvr.de.
John TorousBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Pim CuijpersDepartment of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Jens KleesiekInstitute for AI in Medicine (IKIM), University Hospital Essen, Essen, Germany.
Felix NensaInstitute for AI in Medicine (IKIM), University Hospital Essen, Essen, Germany.
Niels WeberClinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Franziska FaustClinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Tania Josan LalgiClinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Finley Sam MellisClinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Martin TeufelClinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Alexander BäuerleClinic for Psychosomatic Medicine and Psychotherapy, LVR-University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chatbots based on large language models (LLMs) are increasingly used in everyday life. Although concerns about negative impacts on mental health are raised, a synthesis of the research and themes of the growing field of potential mental health harms of LLM-based chatbots has not yet been conducted. For the present scoping review, a PRISMA-based systematic literature search with a validated search string was conducted, identifying N = 3137 articles from five literature databases (ACM, IEEE, PubMed, Science.gov, Google Scholar) and a supplementary search. N = 119 articles were included that (1) focus on LLM-based chatbots, and (2) focus on the harms of use on mental health. Literature was divided into five categories. Conceptual works mention harms based on chatbot limitations (hallucinations, sycophancy, bias), data security issues, and risks for severe or high-risk psychiatric cases (e.g., suicide, psychosis). Vignette studies show that LLM-based chatbots respond inappropriately to mental health queries compared with clinical standards. Cognitive overreliance on chatbots is associated with decreased cognitive and academic performance. Problematic use of LLM-based chatbots, marked by symptoms of emotional or social dependency and withdrawal, correlates with mental health symptoms. Articles on AI psychosis propose several potential links between delusional beliefs and LLM-based chatbot use, such as risks of chatbots reinforcing and validating delusional beliefs.This structured, integrative overview shows that theoretical and empirical work identify various hypothetical and observed harms associated with the use of LLM chatbots in mental health.

Identifiers

PMID42624944
PMCPMC13493897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.