Evidence map›Paper›PMID 42624845›Full record

ArticleNature communications2026

ibSLS as a biobank for democratizing access to multi-omics data and biospecimens from spaceflight research.

Akihito Otsuki, Yuichi Aoki, Risa Okada, Liam Baird, Daisuke Kamimura, Dai Shiba, Eiji Hishinuma, Seizo Koshiba, Fumiki Katsuoka, Kengo Kinoshita and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Akihito Otsuki *Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. akihitootsuki@tohoku.ac.jp.ORCID http://orcid.org/0000-0003-1516-1010
Yuichi Aoki *Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID http://orcid.org/0000-0003-3280-5076
Risa OkadaSpace Environment Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency, Tsukuba, Japan.
Liam BairdAdvanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai, Japan.
Daisuke KamimuraSpace Environment Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency, Tsukuba, Japan.
Dai ShibaSpace Environment Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency, Tsukuba, Japan.ORCID http://orcid.org/0000-0003-3808-5428
Eiji HishinumaTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Seizo KoshibaTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID http://orcid.org/0000-0003-2001-1949
Fumiki KatsuokaTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID http://orcid.org/0000-0003-0939-7887
Kengo KinoshitaTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Takafumi SuzukiTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.ORCID http://orcid.org/0000-0002-3425-8208
Akira UrunoTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Masayuki YamamotoTohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. masayuki.yamamoto.c7@tohoku.ac.jp.ORCID http://orcid.org/0000-0002-9073-9436

Funding

Japan Agency for Medical Research and Development (AMED) JP26tm0135602MEXT | Japan Society for the Promotion of Science (JSPS) 25H01370MEXT | Japan Society for the Promotion of Science (JSPS) 25H01374
6 · The paper itself

Abstract

During spaceflight, astronauts are exposed to extreme conditions such as microgravity, cosmic radiation, and confinement, which can cause a wide range of health problems. To elucidate the molecular mechanisms underlying these issues and to develop intervention strategies for maintaining physiological homeostasis during space missions, space life science research using mouse models is actively conducted on the International Space Station (ISS). However, because of the high cost and technical complexity of spaceflight experiments, it is essential to maximize the scientific value of each mission by ensuring broad accessibility to both data and biospecimens. To this end, we present the integrated biobank for Space Life Science (ibSLS; https://ibsls.megabank.tohoku.ac.jp ), a data-visualization and sample-sharing platform that provides access to transcriptomic and metabolomic datasets generated from Mouse Habitat Unit (MHU) missions conducted by the Japan Aerospace Exploration Agency (JAXA). The platform features a user-friendly interface, tools for cross-mission analysis, and links to human multi-omics databases to support cross-species interpretation. In addition, ibSLS facilitates biospecimen requests to support downstream research. By promoting open access to spaceflight-derived data and biological resources, ibSLS encourages the participation of researchers from diverse fields in space life science.

Indexed as

Biological Specimen BanksSpace FlightAnimalsAstronautsDatabases, FactualHumansJapanMetabolomicsMiceMultiomicsTranscriptomeWeightlessness

Identifiers

PMID42624845
PMCPMC13493919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.