Evidence map›Paper›PMID 42623773›Full record

ArticlePoultry science2026

Growth performance, intestinal morphology, and serum biochemistry of European quail (Coturnix coturnix) fed agro-industrial fruit residue extracts as alternatives to antibiotic growth promoters.

Humberto de Araújo Brito Filho, Adiel Vieira de Lima, Cícero Jorge de Medeiros, Apolônio Gomes Ribeiro, Edijanio Galdino da Silva, Carlos Henriquedo Nascimento, Aline Beatriz Rodrigues, Paloma Eduarda Lopes de Souza, Ricardo Romão Guerra, Amanda Itoh de Medeiros and 5 more

Abstract read
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Humberto de Araújo Brito FilhoDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Adiel Vieira de LimaDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Cícero Jorge de MedeirosDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Apolônio Gomes RibeiroDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Edijanio Galdino da SilvaDepartment of Veterinary Sciences, Federal University of Paraíba, Areia, PB, Brazil.
Carlos Henriquedo NascimentoDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Aline Beatriz RodriguesDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Paloma Eduarda Lopes de SouzaDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Ricardo Romão GuerraDepartment of Veterinary Sciences, Federal University of Paraíba, Areia, PB, Brazil.
Amanda Itoh de MedeirosDepartment of Veterinary Sciences, Federal University of Paraíba, Areia, PB, Brazil.
Thácyla Beatriz Duarte CorreiaDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.
Matheus Ramalho de LimaAnimal Science Department, Universidade Federal Rural do Semi-Árido, Mossoró, RN, Brazil.
Leonardo Augusto Fonseca PascoalAnimal Science Department, Universidade Federal da Paraíba, Bananerias-PB, Brazil.
Lucas Rannier Ribeiro Antonino CarvalhoDepartment of Physiology and Pharmacology, Karolinska Institutet, Biomedicum 5B, Solnavägen 9, Stockholm, S-171 77, Sweden. Electronic address: lucas.carvalho@ki.se.
Fernando Guilherme Perazzo CostaDepartment of Animal Science, Federal University of Paraiba, Highway PB-079, Areia - PB, 58397-000, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effects of dietary supplementation with agro-industrial fruit residue extracts as alternatives to antibiotic growth promoters on performance, intestinal histomorphometry, and serum biochemical parameters of European quail (Coturnix coturnix). A total of 250 one-day-old birds were distributed in a completely randomized design with five treatments: positive control (bacitracin zinc, 500 g/t), negative control, and diets supplemented with pineapple (Ananas comosus) extract (900 ppm), acerola (Malpighia emarginata) extract (1,600 ppm), or cajá (Spondias mombin) extract (900 ppm) for 35 days. Data were subjected to analysis of variance (ANOVA), and means were compared using Tukey's test at a 5% significance level. From 1 to 14 days, quail fed cajá extract showed lower weight gain compared with the negative control, with no differences for feed intake or feed conversion. From 15 to 35 days, feed intake was lower in birds receiving cajá compared with both controls. At 35 days, final body weight was lower in the cajá group, whereas pineapple and acerola treatments did not differ from the controls. In the ileum, villus height, villus area, and villus:crypt ratio were higher in birds fed pineapple and acerola extracts compared with cajá. Cajá extract resulted in lower villus height and villus:crypt ratio and higher crypt depth. In the duodenum and jejunum, fewer differences were observed among treatments. Serum biochemical parameters were affected by treatments. Birds fed cajá extract showed lower glucose, phosphorus, total protein, and albumin levels. Aspartate aminotransferase and alkaline phosphatase activities were higher in birds fed acerola extract. No differences were observed for triglycerides, creatinine, uric acid, alanine aminotransferase, or γ-glutamyl transferase. In conclusion, pineapple extract at 900 ppm and acerola extract at 1,600 ppm maintained performance and improved ileal morphology, whereas cajá extract at 900 ppm resulted in lower performance, altered intestinal morphology, and reduced serum biochemical parameters.

Indexed as

Fruit residuesIntestinal healthNatural additivesPerformanceQuail

Identifiers

PMID42623773
PMCPMC13524480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.