Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Melvin Alappat *Institute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0009-0007-9392-6994
Marta Anna Mazurkiewicz *Institute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0009-0007-7996-429X
Iris ZambounisInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.
Alice MastrangeloInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0009-0009-0415-0325
Vicente Mario Algaba MartínezInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0000-0002-7027-8572
Thomas GramppInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.
Francesco PriscoLaboratory for Animal Model Pathology, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich CH-8057, Switzerland.
Anja KiparLaboratory for Animal Model Pathology, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0000-0001-7289-3459
Alexandre PicardCenter for Integrative Genomics, University of Lausanne, Lausanne CH-1015, Switzerland.
Musadiq A BhatInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0000-0002-0894-9996
Dietmar BenkeInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0000-0003-1846-4711
Hanns Ulrich ZeilhoferInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0000-0001-6954-4629
Bernard ThorensCenter for Integrative Genomics, University of Lausanne, Lausanne CH-1015, Switzerland.ORCID 0000-0002-3738-0129
Sevasti GaspariInstitute of Pharmacology and Toxicology, University of Zurich, Zurich CH-8057, Switzerland.ORCID 0000-0002-0596-4840
Funding
EC | Horizon Europe | Excellent Science | HORIZON EUROPE European Research Council (ERC) 694798Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 208875Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 310030-182496
6 · The paper itself
Abstract
The counterregulatory response (CRR) to hypoglycemia-critically depending on pancreatic glucagon secretion-is a fundamental, evolutionarily conserved homeostatic mechanism orchestrated by the central nervous system (CNS) to ensure survival during glucose scarcity.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Tmem117, an oligodendrocyte-enriched regulator of NCX activity, links myelin homeostasis to counterregulation and metabolic health. · full record | OpenQuestion