ArticleJournal of cardiovascular electrophysiology2026
Spatial Clustering and High-Frequency Characteristics of Residual Conduction in the Left Atrial Posterior Wall.
Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLeft atrial posterior wall (LAPW) isolation is frequently limited by residual conduction (RC) despite apparently complete endocardial linear lesions. Such conduction may involve interbundle connections between the septo-atrial and septo-pulmonary bundles or deeper conduction pathways. However, the spatial distribution and electrophysiological characteristics of these functionally defined RCs remain incompletely understood in clinical settings.
methodsTwenty-two patients undergoing LAPW isolation were prospectively studied. Among 22 patients, 11 required additional ablation after a confirmed roof and bottom line block, in whom residual electrograms were mapped using peak frequency (PF) analysis with the EnSite system. The LAPW was divided into nine predefined anatomical segments, and segments requiring ablation to achieve complete isolation were defined as RC-positive.
resultsRC-positive segments predominantly clustered in the mid-central region (82%), whereas other regions were less frequently involved. PF was significantly higher in RC-positive than in RC-negative segments (460 [380-520] vs. 300 [250-400] Hz; p < 0.001), and a PF cutoff of 365 Hz demonstrated moderate discriminatory performance (area under the curve, 0.796). RC-positive segments exhibited greater electrogram fractionation during both atrial fibrillation and atrial pacing, consistent with increased local conduction complexity. Targeted ablation at these sites resulted in complete LAPW isolation in all cases without complications.
conclusionFunctionally defined RC within the LAPW exhibits a nonuniform spatial distribution with mid-central clustering and distinct electrophysiological characteristics. PF-based mapping may facilitate targeted identification of these regions and provide functional insights into potential non-endocardial conduction pathways in incomplete LAPW isolation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.