Evidence map›Paper›PMID 42623427›Full record

SynthesisJournal of clinical microbiology2026

MIC-based tuberculosis drug susceptibility testing using Sensititre MYCOTB: a diagnostic accuracy meta-analysis.

Daniel Raj D, Mukesh Kumar G, Jitendra Singh, Sabir Ali, Shaina Gaikwad, Tharani Mohankumar, Swathi S, Shashank Purwar, Debasis Biswas, Anand Kumar Maurya and 3 more

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of clinical microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Daniel Raj DMedical Laboratory Technology (Microbiology), AIIMS, Bhopal, Madhya Pradesh, India.ORCID 0009-0006-8187-3840
Mukesh Kumar GPsychiatric Nursing, AIIMS, Bhopal, Madhya Pradesh, India.
Jitendra SinghDepartment of Translational Medicine, AIIMS, Bhopal, Madhya Pradesh, India.ORCID 0000-0001-5626-6076
Sabir AliMedical Research Unit (MRU), AIIMS, Bhopal, Madhya Pradesh, India.
Shaina GaikwadDepartment of Microbiology, AIIMS, Bhopal, Madhya Pradesh, India.
Tharani MohankumarMedical Laboratory Technology (Microbiology), AIIMS, Bhopal, Madhya Pradesh, India.
Swathi SMedical Laboratory Technology (Microbiology), AIIMS, Bhopal, Madhya Pradesh, India.
Shashank PurwarDepartment of Microbiology, AIIMS, Bhopal, Madhya Pradesh, India.
Debasis BiswasDepartment of Microbiology, AIIMS, Bhopal, Madhya Pradesh, India.
Anand Kumar MauryaDepartment of Microbiology, AIIMS, Bhopal, Madhya Pradesh, India.ORCID 0000-0002-4827-919X
Sanjit SahDepartment of Paediatrics, Dr D.Y. Patil Medical College, Hospital and Research Centre. Dr. D.Y. Patil Vidyapeeth (Deemed-to-be-University), Pune, Maharashtra, India.
Aroop MohantyDepartment of Microbiology, AIIMS, Gorakhpur, Uttar Pradesh, India.ORCID 0000-0001-5634-5014
Rachana MehtaClinical Microbiology, RDC, Manav Rachna International Institute of Research and Studies, Faridabad, Haryana, India.ORCID 0000-0003-4771-4089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate drug susceptibility testing (DST) is crucial for designing effective regimens for multidrug-resistant (MDR) and pre-extensively drug-resistant tuberculosis (pre-XDR TB). Sensititre MYCOTB enables simultaneous determination of minimum inhibitory concentrations (MICs) for multiple drugs, but its diagnostic performance varies across studies. This meta-analysis evaluated the diagnostic performance of Sensititre MYCOTB for key MDR and pre-XDR TB drugs. The protocol was registered in PROSPERO (CRD420251230599). PubMed, Cochrane, Google Scholar, Scopus, ONOS, Web of Science, ScienceDirect, and registries were systematically searched for studies published between 2010 and 2025. Studies comparing the Sensititre MYCOTB with reference DST for

Indexed as

Antitubercular AgentsMycobacterium tuberculosisHumansMicrobial Sensitivity TestsSensitivity and SpecificityTuberculosis, Multidrug-ResistantAntitubercular Agentsgold standard DSTmethod comparisonphenotypic drug susceptibility testsensititre MYCOTB AST plate

Identifiers

PMID42623427
PMCPMC13556204

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.