Observational studyThe Australian and New Zealand journal of psychiatry2026
Hospitalisation and mortality outcomes after second COVID-19 vaccination among Australians living with severe mental illness: Findings from a matched case-control study using national data linkage.
Observational study in The Australian and New Zealand journal of psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the proportion of Australians living with severe mental illness (target group) and the general population (comparator group) who received the first, second, and third doses of the COVID-19 vaccination between 22 February 2021 and 30 June 2022; examine the odds of any, non-psychiatric, and COVID-19-related hospitalisations within 12 months of the second vaccination; and examine the odds of all-cause and COVID-19-specific mortality within 12 months.
methodsWe used a retrospective 1:4 age- and sex-matched case-control design. Subgroup analysis of individuals aged ⩾65 years old was also undertaken. This study used de-identified, linked administrative data from the Australian Immunisation Register, Pharmaceutical Benefits Scheme, Medicare Benefits Schedule, National Death Index, Demography data, and hospital records.
resultsThe cohort included 375,335 individuals living with severe mental illness and 1,373,231 comparators. Between 22 February 2021 and 30 June 2022, the proportion of target group members receiving the first, second, and third doses was significantly lower than the comparators, albeit still high, and with a shorter average time between vaccinations. Adjusted odds of hospitalisation in the target group within 12 months of the second vaccination were 14.0 (95% CI = 13.8-14.2) for any, 9.7 (95% CI = 9.6-9.8) for non-psychiatric, and 19.0 (95% CI = 17.7-20.3) for COVID-19-related hospitalisations. Adjusted odds of all-cause mortality were 3.1 (95% CI = 3.0-3.1) and 9.4 (95% CI = 7.7-11.5) for COVID-19-related mortality.
conclusionsPeople with severe mental illness had significantly poorer hospitalisation and mortality outcomes after their second vaccination, highlighting persistent gaps in access and equity of care for this vulnerable population. STUDY REGISTRATION: ACTRN12624000117516.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.