ArticlemBio2026
Novelty, diversity, and genetic dark matter in enterococci of invertebrates.
Bruna F Sgardioli, Matthew C Phillips, Arjun Miklos, Kailey Fleiszig-Evans, Abigail L Manson, Suelen Scarpa de Mello, Terrance Shea, Aysun Urhan, Ryan Whipple, Rauf Salamzade and 5 more
Abstract read
In one paragraphArticle in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Bruna F Sgardioli *Faculty of Agricultural and Environmental Sciences, University of the Azores, Angra do Heroísmo, Portugal.
Matthew C Phillips *Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-9329-5455 Arjun MiklosInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.
Kailey Fleiszig-EvansInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.
Abigail L MansonInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.ORCID 0000-0002-3800-0714 Terrance SheaInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.
Aysun UrhanInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.
Ryan WhippleHarvard Medical School, Boston, Massachusetts, USA.
Rauf SalamzadeInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.
Jasper SandersInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.
Paulo A V BorgesUniversity of Azores, CE3C-Centre for Ecology, Evolution and Environmental Changes, Azorean Biodiversity Group, CHANGE-Global Change and Sustainability Institute, School of Agricultural and Environmental Sciences, Angra do Heroísmo, Azores, Portugal.ORCID 0000-0002-8448-7623 Maria de Lurdes Nunes Enes DapkeviciusFaculty of Agricultural and Environmental Sciences, University of the Azores, Angra do Heroísmo, Portugal.ORCID 0000-0003-2146-5627 Ashlee M EarlInfectious Disease and Microbiome Program, Broad Institute, Cambridge, Massachusetts, USA.ORCID 0000-0001-7857-9145 Funding
Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI EARL, ASHLEE MIRIAM · 2014 to 2024
$66.5MTechnical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI David C Hooper · 2009 to 2026
$39.4MINFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1MFundação para a Ciência e a Tecnologia UID/00153/2023Fundação para a Ciência e a Tecnologia UIDB/00153/2020Fundação para a Ciência e a Tecnologia UID/CTV/00153/2019National Institute of Allergy and Infectious Diseases P01AI 083214National Institute of Allergy and Infectious Diseases T32AI007061National Institute of Allergy and Infectious Diseases U19AI110818NIAID NIH HHS P01 AI083214NIAID NIH HHS T32 AI007061NIAID NIH HHS U19 AI110818
6 · The paper itselfAbstract
Enterococci appear to have originated in the guts of early terrestrializing arthropods and invertebrates over 425 million years ago-hosts that are now highly diverse and widespread in nature today. Yet most knowledge of the genus comes from human infection-associated lineages with genomes swollen by the recent accretion of foreign DNA conveyed by mobile elements. Because invertebrates dominate terrestrial animal diversity and biomass, they would be predicted to constitute a major but little-explored reservoir of enterococcal diversity. We therefore systematically examined
Indexed as
EnterococcusGenetic VariationInvertebratesAnimalsGenome, BacterialHumansPhylogenyWhole Genome Sequencingantibiotic resistanceEnterococcusevolutionary biologygenomicshost associationinvertebrate microbiomemicrobial ecologyvertebrate microbiome
Identifiers
PMID42623063
PMCPMC13556245
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