ArticleDiscover oncology2026
Global research trends and emerging hotspots of immune checkpoint inhibitors in gastric cancer from 2015 to 2025.
Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImmune checkpoint inhibitors (ICIs) have emerged as an important therapeutic strategy for gastric cancer. However, the rapid expansion of related research has made it challenging to comprehensively understand its developmental patterns and emerging directions. This study aimed to systematically evaluate research trends and hotspots in ICIs for gastric cancer using bibliometric methods.
methodsA comprehensive literature search was conducted in the Web of Science Core Collection, covering publications from January 1, 2015, to October 28, 2025. Bibliometric analysis was performed using CiteSpace, VOSviewer, and Scimago Graphica to assess publication trends, collaborative networks, influential authors and journals, co-cited references, and keyword evolution.
resultsA total of 1440 publications were included. The overall research output exhibited a sustained growth trend. Global collaboration networks were dominated by a limited number of core countries and institutions. Keyword and reference analyses revealed that major research hotspots evolved from clinical efficacy validation to biomarker-driven precision stratification and, more recently, to tumor microenvironment modulation and combination therapy strategies.
conclusionsThis bibliometric analysis provides a structured overview of the research landscape of ICIs in gastric cancer. The findings highlight the progressive shift of research focus toward precision immunotherapy and mechanistic exploration, offering insights that may inform future basic and clinical research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.