Evidence map›Paper›PMID 42622553›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2026

Kinematic Features of Laryngeal Motor Control in Parkinson's Disease.

Dilys C Tan, Hasini R Weerathunge, Manuel Diaz-Cadiz, Cara E Stepp, Jenny Vojtech

Abstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Dilys C TanDepartment of Speech, Language & Hearing Sciences, Boston University, MA.
Hasini R WeerathungeDepartment of Speech, Language & Hearing Sciences, Boston University, MA.ORCID 0000-0002-0240-9104
Manuel Diaz-CadizDepartment of Speech, Language & Hearing Sciences, Boston University, MA.
Cara E SteppDepartment of Speech, Language & Hearing Sciences, Boston University, MA.ORCID 0000-0002-8045-252X
Jenny VojtechDepartment of Speech, Language & Hearing Sciences, Boston University, MA.ORCID 0000-0002-0583-0228

Funding

Use of ambulatory biofeedback to improve behavioral treatment of vocal hyperfunctionP50DC015446 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI Robert E Hillman · 2017 to 2026
$25.5M
Objective Measures for Clinical Assessment of Voice DisordersR01DC015570 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI STEPP, CARA E. · 2016 to 2025
$4.8M
NIDCD NIH HHS P50 DC015446NIDCD NIH HHS R01 DC015570
6 · The paper itself

Abstract

purposeLaryngeal kinematics were examined under high-speed videoendoscopy to examine laryngeal motor control of persons with Parkinson's disease (PD).

methodA retrospective analysis was performed on 24 people with idiopathic PD and 24 age- and sex-matched controls as they produced repetitions of the utterance /ifi/ at self-induced levels of vocal effort (typical, mild, moderate, and maximum effort). Two kinematic measures of laryngeal motor control were measured during vocal fold adduction: spatiotemporal index (STI; adductory variability across repeated utterances) and asymmetry index (AI; ratio of deceleration to acceleration of adduction). Mixed-effects analysis of variance models were constructed to determine the main effects of group (PD, control), self-induced level of vocal effort, and their interaction.

resultsStatistically significant main effects of group were found for STI, but not AI. No statistically significant effects of vocal effort level or its interaction with group were observed for either measure.

conclusionsLarger STIs in people with PD are consistent with the increased production variability observed in other speech articulators. Neither laryngeal kinematic measure was modulated by vocal effort level. These findings indicate that the STI was sensitive to differences in laryngeal motor control impairment between people with and without PD.

Indexed as

Laryngeal MusclesLarynxParkinson DiseaseSpeechAgedBiomechanical PhenomenaCase-Control StudiesFemaleHumansLaryngoscopyMaleMiddle AgedRetrospective StudiesVideo RecordingVocal Cords

Identifiers

PMID42622553
PMCPMC13678646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.