Evidence map›Paper›PMID 42622436›Full record

ArticlemSystems2026

Age-adjusted machine learning identifies facial skin microbes associated with skin quality among Korean women.

Sangbeen Park, Hye-Been Kim, Hyunsoo Ahn, Geunyeong Lee, Woomin Song, Misun Kim, Eunjin Park, Byung Sun Yu, Miyang Han, Seyoung Mun and 5 more

Abstract read
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sangbeen Park *Department of Life Sciences, Pohang University of Science and Technology, Pohang, Korea.ORCID 0009-0007-5323-9209
Hye-Been Kim *Research and Innovation Center, COSMAX BTI, Seongnam, Republic of Korea.
Hyunsoo Ahn *Graduate School of Artificial Intelligence, Pohang University of Science and Technology, Pohang, Republic of Korea.ORCID 0000-0003-2232-1983
Geunyeong LeeDivision of Interdisciplinary Bioscience & Bioengineering, Pohang University of Science and Technology, Pohang, Republic of Korea.
Woomin SongDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Korea.
Misun KimResearch and Innovation Center, COSMAX BTI, Seongnam, Republic of Korea.
Eunjin ParkResearch and Innovation Center, COSMAX BTI, Seongnam, Republic of Korea.
Byung Sun YuDepartment of Biomedical Sciences, College of Bio-convergence, Dankook University, Cheonan, Republic of Korea.
Miyang HanDepartment of Biomedical Sciences, College of Bio-convergence, Dankook University, Cheonan, Republic of Korea.
Seyoung MunDepartment of Microbiology, College of Science & Technology, Dankook University, Cheonan, Republic of Korea.
Dong-Geol LeeResearch and Innovation Center, COSMAX BTI, Seongnam, Republic of Korea.
Chun Ho ParkResearch and Innovation Center, COSMAX BTI, Seongnam, Republic of Korea.
Seunghyun KangResearch and Innovation Center, COSMAX, Seongnam, Republic of Korea.ORCID 0000-0002-9318-8318
HyungWoo JoResearch and Innovation Center, COSMAX BTI, Seongnam, Republic of Korea.ORCID 0000-0001-7727-5238
Sanguk KimDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Korea.ORCID 0000-0002-3449-3814

Funding

Institute for Information and Communications Technology Promotion RS-2019-II191906National Research Foundation of Korea RS-2025-16070008, RS-2026-25472972
6 · The paper itself

Abstract

Recognizing specific microbes that significantly influence skin quality is becoming an essential aspect of personalized skincare. However, conventional large-scale cohort skin microbiome studies often overlook important confounders, such as age, leading to missing meaningful microbe-skin relationships. In this study, we developed an age-adjusted machine learning (AAML) framework to identify microbial candidates associated with skin quality by determining optimal age ranges that enhance age-independent signals of skin microbes. It allowed the identification of distinct age groups that clearly explain specific skin microbial effects, as well as potential microbes showing notable age-independent links to skin quality, which were not observed in analyses across the entire age spectrum. In particular,

Indexed as

FaceMachine LearningSkinSkin MicrobiomeAdultAgedAge FactorsCorynebacteriumFemaleHumansMicrobiotaMiddle AgedRepublic of KoreaYoung Adultagebioinformaticscosmetologyskin microbiomeskin quality

Identifiers

PMID42622436
PMCPMC13595949

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.