Evidence map›Paper›PMID 42622414›Full record

ArticleMicrobiology spectrum2026

Rapid phage susceptibility determination using a semi-automated bioluminescent ATP assay.

Houssein Chalhoub, Valéry Daubie, Hafid Dahma, Bob Blasdel, Isabelle Tytgat, Johan Quintens, Olivier Vandenberg, Marie Hallin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Houssein ChalhoubCenter for Environmental and Occupational Health, Ecole de Santé Publique - Université Libre de Bruxelles, Brussels, Belgium.
Valéry DaubieResearch & Innovation Unit, Laboratoire Hospitalier Universitaire de Bruxelles - Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles, Brussels, Belgium.ORCID 0000-0002-5645-8294
Hafid DahmaResearch & Innovation Unit, Laboratoire Hospitalier Universitaire de Bruxelles - Universitair Laboratorium Brussel (LHUB-ULB), Université Libre de Bruxelles, Brussels, Belgium.ORCID 0000-0003-0301-8153
Bob BlasdelInteliphage, Mont-St-Guibert, Belgium.ORCID 0000-0003-0521-1803
Isabelle TytgatInteliphage, Mont-St-Guibert, Belgium.
Johan QuintensInteliphage, Mont-St-Guibert, Belgium.ORCID 0009-0000-1854-0003
Olivier VandenbergCenter for Environmental and Occupational Health, Ecole de Santé Publique - Université Libre de Bruxelles, Brussels, Belgium.ORCID 0000-0003-0484-4502
Marie HallinCenter for Environmental and Occupational Health, Ecole de Santé Publique - Université Libre de Bruxelles, Brussels, Belgium.ORCID 0000-0003-4544-0635

Funding

Région Wallonne WIN2WAL program 1910081
6 · The paper itself

Abstract

Antimicrobial resistance is a major threat to human health. Phage therapy is a promising alternative to antibiotics, yet routine diagnostic tools capable of rapidly determining phage susceptibility are lacking. Our goal was to develop a diagnostic tool providing easy-to-interpret IMPORTANCE: The lack of reproducible user-friendly phage susceptibility testing that can timely inform clinical decisions remains a major barrier to the routine clinical use of phages. We developed a high-throughput, semi-automated prototype that delivers easy-to-interpret phage susceptibility results for four bacterial species within 5 h in a "real-life" clinical flow. However, the correlation between

Indexed as

Adenosine TriphosphateBacteriaBacteriophagesLuminescent MeasurementsEscherichia coliHumansKlebsiella pneumoniaePhage TherapyPseudomonas aeruginosaReproducibility of ResultsSensitivity and SpecificityStaphylococcus aureusAdenosine Triphosphatebacteriophagesclinical microbiologyphage susceptibility testing

Identifiers

PMID42622414
PMCPMC13689462

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.