Evidence map›Paper›PMID 42622054›Full record

ArticleRheumatology advances in practice2026

Impact of social deprivation on cancer occurrence and cardiovascular events in systemic sclerosis.

Amy Turnbull, Ula Tymoszuk, Fiona A Pearce, Benjamin G Faber, Shaney L Barratt, Sue Farrington, Nick Jeffries-Owen, Ami A Shah, Clare Pain, Christopher P Denton and 1 more

Abstract read
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In one paragraph

Article in Rheumatology advances in practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amy TurnbullBristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0009-0007-1443-9320
Ula TymoszukScleroderma and Raynaud's UK, London, UK.ORCID https://orcid.org/0000-0002-0781-2752
Fiona A PearceLifespan and Population Health, School of Medicine, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0003-2884-1998
Benjamin G FaberDepartment of Rheumatology, North Bristol NHS Trust, Bristol, UK.ORCID https://orcid.org/0000-0003-4102-0190
Shaney L BarrattDepartment of Respiratory Medicine, North Bristol NHS Trust, Bristol, UK.ORCID https://orcid.org/0000-0003-3067-7349
Sue FarringtonScleroderma and Raynaud's UK, London, UK.
Nick Jeffries-OwenScleroderma and Raynaud's UK, London, UK.
Ami A ShahDivision of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-1139-2009
Clare PainDepartment of Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.ORCID https://orcid.org/0000-0003-4965-3259
Christopher P DentonCentre for Rheumatology and Connective Tissue Diseases, Division of Medicine, University College London, London, UK.ORCID https://orcid.org/0000-0003-3975-8938
John D PaulingDepartment of Rheumatology, North Bristol NHS Trust, Bristol, UK.ORCID https://orcid.org/0000-0002-2793-2364

Funding

Wellcome Trust
6 · The paper itself

Abstract

Objectives: Cardiovascular events (CVEs) and malignancy are important non-disease-related causes of mortality in SSc. We evaluated secondary care utilisation and impact of deprivation on comorbidity patterns in SSc in England. Methods: We analysed secondary care service utilisation in SSc using Hospital Episode Statistics for England for 2024. Cases were linked to Index of Multiple Deprivation deciles. Myocardial infarction (MI), lung cancer, breast cancer, melanoma rates and short-term all-cause mortality were explored, alongside comparisons with SLE and RA. Results: In 2024, ≈6000 people with SSc (84.6% female, 70.8% between 51 and 80 years of age, 73.3% White ethnicity) accessed secondary healthcare in England. Older SSc patients were overrepresented in less-deprived postcodes ( Conclusion: Secondary care utilisation in SSc suggests less deprived SSc patients are older. All-cause mortality is higher in SSc patients receiving cancer care. Cancer occurrence is higher in SSc compared with SLE and RA. Our findings might support healthcare services planning and cancer screening for SSc in England.

Indexed as

cancercardiovascularcomorbiditiessocial deprivationsystemic sclerosis

Identifiers

PMID42622054
PMCPMC13489704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.