Evidence map›Paper›PMID 42622013›Full record

ArticleCureus2026

Beyond Apical Ballooning: A Rare Focal Takotsubo Syndrome Variant Following Interscalene Block-Associated Airway Obstruction.

Gonzalo J Martinez-Ruiz, Gerardo E Martinez-Arroyo, Frankie Alvarado-Abraham, Jonathan Cordero-Jimenez, Jorge J Ballester-Maldonado

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gonzalo J Martinez-RuizInternal Medicine, Universidad Central del Caribe (UCC) School of Medicine, Bayamón, USA.
Gerardo E Martinez-ArroyoInternal Medicine, Universidad Central del Caribe (UCC) School of Medicine, Bayamón, USA.
Frankie Alvarado-AbrahamCritical Care Medicine, Hospital Pavía Arecibo, Arecibo, USA.
Jonathan Cordero-JimenezInterventional Cardiology, Hospital Pavía Arecibo, Arecibo, USA.
Jorge J Ballester-MaldonadoCardiology, Hospital Pavía Arecibo, Arecibo, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo syndrome (TTS) is a transient stress-induced cardiomyopathy that typically presents with apical ballooning; focal variants are rare and may closely mimic acute coronary syndromes. We present the case of a 74-year-old woman who developed acute hypoxemic respiratory failure secondary to vocal cord and phrenic nerve paralysis following an interscalene block. During hospitalization, she exhibited isolated troponin elevation without chest pain or electrocardiographic changes. Coronary angiography demonstrated nonobstructive coronary arteries, while ventriculography revealed focal lateral wall hypokinesis consistent with focal TTS. Initial management included full acute coronary syndrome therapy, which was subsequently de-escalated after the diagnosis was established. Acute airway obstruction is an uncommon trigger, underscoring the role of catecholamine-mediated myocardial stunning and the importance of early recognition to avoid unnecessary interventions and guide appropriate management.

Indexed as

cardiomyopathycoronary angiographyechocardiographymyocardial infarctiontakotsubo syndrome

Identifiers

PMID42622013
PMCPMC13489553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.