Evidence map›Paper›PMID 42621917›Full record

ArticleFrontiers in allergy2026

Proteomic profiling of

Sandra Sivill, Jose Carlos Hernández-Walias, Juan Manuel Igea, Jose Alejandro Lemus Calderon, Ana Maria Navarro-Pulido, Carmen Rondon, Beatriz Fernandez Parra, Magdalena Lluch-Bernal, M Teresa Dordal Culla, Fernando Pineda and 3 more

Abstract read
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In one paragraph

Article in Frontiers in allergy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sandra SivillInmunotek, S.L., R&D Department, Alcalá de Henares, Madrid, Spain.
Jose Carlos Hernández-WaliasInmunotek, S.L., R&D Department, Alcalá de Henares, Madrid, Spain.
Juan Manuel IgeaAllergy Unit, Clínica Alergoasma, Salamanca, Spain.
Jose Alejandro Lemus CalderonAllergy Unit, Hospital General de Villarobledo, Albacete, Spain.
Ana Maria Navarro-PulidoAllergy Unit, Hospital Universitario Virgen Macarena, Sevilla, Spain.
Carmen RondonAllergy Unit, Hospital Regional Universitario de Malaga, Malaga, Spain.
Beatriz Fernandez ParraAllergy Unit, Hospital Universitario El Bierzo, Ponferrada/León, Spain.
Magdalena Lluch-BernalAllergy Unit, Hospital Universitario La Paz, Madrid, Spain.
M Teresa Dordal CullaAllergy Unit, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
Fernando PinedaInmunotek, S.L., R&D Department, Alcalá de Henares, Madrid, Spain.
Jose Luis SubizaInmunotek, S.L., R&D Department, Alcalá de Henares, Madrid, Spain.
Salvador IborraInmunotek, S.L., R&D Department, Alcalá de Henares, Madrid, Spain.
Jose F CantilloInmunotek, S.L., R&D Department, Alcalá de Henares, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diagnosis and allergen-specific immunotherapy for Mediterranean allergy rely on extracts standardized to group-1 allergens, such as Cup a 1 from Objective: To characterize and compare the allergen and IgE-binding protein composition of Methods: Pollen extracts were analyzed using SDS-PAGE, two-dimensional electrophoresis (2-DE), Western blotting (WB), and mass spectrometry (MS). 241 patients with allergic rhinitis and/or conjunctivitis from seven Spanish regions underwent skin prick testing and specific IgE for extracts and Jun o 1/Cup a 1, by ELISA. Cross-reactivity was assessed by competitive ELISA and WB inhibition. Results: Proteomics and 2-DE showed a more complex protein profile in Conclusion:

Indexed as

allergen cross-reactivityCupressaceae allergyCupressus arizonicaIgE sensitizationJuniperus oxycedruspollen IgE-binding proteinsproteomics

Identifiers

PMID42621917
PMCPMC13487880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.