ArticleACS ES&T air2026
Understanding the Temporal Evolution of Isoprene Organosulfates Using a Novel Hydrophilic Interaction Chromatography Method.
Article in ACS ES&T air, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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16 authors.
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Abstract
Organosulfates (OSs) form a significant component of secondary organic aerosol (SOA) in the atmosphere. Previously, their measurement using reversed-phase liquid chromatography-high-resolution mass spectrometry (RPLC-HRMS) has led to poor retention and significant matrix effects. Hydrophilic interaction liquid chromatography (HILIC) provides improved retention of polar OSs, such as those formed from isoprene oxidation, and reduced matrix effects. Studies employing HILIC predominantly use gradient elution to separate OSs with varying polarities. HILIC, however, is very sensitive to changes in the water layer within the column, which facilitates separation, meaning the column needs to be thoroughly equilibrated before each injection, significantly increasing analysis time, cost, and solvent waste. The work presented here describes the development of an isocratic HILIC method to analyze OSs in complex ambient PM
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