Evidence map›Paper›PMID 42621831›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2026

Conformationally constrained 6‑aryl‑1‑(3,4,5‑trimethoxyphenyl)-1

Zhu Guo, Yujing Zhang, Ping Zou, Caiyun Sun, Liya Cui, Gang Wang, Chao Wang

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhu GuoDepartment of Spinal Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yujing ZhangThe Affiliated Cardiovascular Hospital of Qingdao University, Qingdao University, Qingdao, China.
Ping ZouThe Affiliated Cardiovascular Hospital of Qingdao University, Qingdao University, Qingdao, China.
Caiyun SunThe Affiliated Cardiovascular Hospital of Qingdao University, Qingdao University, Qingdao, China.
Liya CuiThe Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Gang WangThe Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Chao WangThe Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel class of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1

Indexed as

Antineoplastic AgentsDrug DesignMicrotubulesPyrazinesPyrazolesTubulin ModulatorsApoptosisCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMolecular ConformationMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsPyrazinesPyrazolesTubulinTubulin Modulatorsantiproliferative activityMicrotubule destabilizerpyrazolo[3,4-b]pyrazinestructure activity relationship

Identifiers

PMID42621831
PMCPMC13495038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.