ArticleTrends in hearing
The Failure Index as Marker of the Neural Health Profile in MED-EL CI Users: A Retrospective Analysis.
Article in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cochlear implants (CIs) enable hearing via direct electrical stimulation of the spiral ganglion neurons (SGN). Outcomes with a CI depend, in part, on the number and excitability of the SGNs. In an animal model, we introduced the Failure Index (FI) as an electrically-evoked compound action potential (eCAP)-derived marker of cochlear health. The FI informs about the presence, site, and size of SGN lesions. Here, we translated the FI to clinical recordings from human MED-EL CI users. In this retrospective study, we included patient data recorded between 2016 and 2024 from 199 ears with postlingual hearing loss and 79 ears with prelingual hearing loss. The averaged FI values over all contacts of the array were stable within the analysis period (3
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