ArticleFrontiers in neurology2026
Impact of cavernous internal carotid artery tortuosity on technical and clinical outcomes in mechanical thrombectomy for acute ischemic stroke: a single-center retrospective study.
Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and purpose: Cavernous internal carotid artery (ICA) tortuosity may hinder catheter navigation during mechanical thrombectomy (MT) for acute ischemic stroke (AIS). However, its impact on procedural and clinical outcomes remains unclear. This study evaluated the association between cavernous ICA tortuosity, classified by the Lin grading system, and outcomes in patients undergoing MT for middle cerebral artery (MCA) occlusion. Methods: In this single-center retrospective study, 425 patients with MCA occlusion treated with MT were included. Patients were categorized as tortuous ( Results: Tortuous anatomy was associated with lower first-pass success (43.9% vs. 54.1%; Conclusion: Cavernous ICA tortuosity is an independent predictor of reduced first-pass success and worse early outcomes in MT. Aspiration may be a more effective strategy in this subgroup, supporting the importance of pre-procedural anatomical assessment.
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