Evidence map›Paper›PMID 42621427›Full record

ArticleJournal of hand surgery global online2026

The Impact of Emerging Therapies and Declining Physician Reimbursement on Dupuytren Disease Treatment: A 21 Year Review.

Evan H Richman, Dylan Rakowski, Alexander Lauder

Abstract read
In one paragraph

Article in Journal of hand surgery global online, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Evan H RichmanDepartment of Orthopedic Surgery, University of Colorado School of Medicine, Aurora, CO.
Dylan RakowskiDepartment of Orthopedic Surgery, University of Colorado School of Medicine, Aurora, CO.
Alexander LauderDepartment of Orthopedic Surgery, University of Colorado School of Medicine, Aurora, CO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the trends in treatment and physician reimbursement for Dupuytren contracture (DC) within the Medicare population over a 21-year period, with a focus on how the introduction of collagenase Methods: Medicare Part B data from 2000 to 2021 were analyzed to assess procedure volumes, charges, and reimbursements using Current Procedural Terminology codes for percutaneous needle fasciotomy, Open fasciotomy/fasciectomy, and CCH injection. Inflation-adjusted reimbursement rates were calculated. Google Trends data from 2012 to 2023 were analyzed to assess public interest in DC and its treatments. Results: From 2000 to 2021, treatment volumes for DC increased by 167%. Over this period, treatment patterns shifted substantially away from surgical management: open fasciectomy accounted for 96% of all procedures in 2000 but declined to 59% in 2021, whereas CCH emerged as a major treatment modality, accounting for 27% of all procedures by 2021. Enrollment-adjusted procedure volumes increased by 468% for percutaneous needle fasciotomy, 19% for CCH, and 2% for open fasciectomy. Inflation-adjusted physician reimbursement declined by 42% across all Dupuytren contracture treatments, with the greatest decrease observed for percutaneous needle fasciotomy (32%) and the smallest for CCH (5%). Public interest, as assessed by Google Trends, increased by 525% for DC-related searches, including a 1,033% increase in searches related to CCH. Conclusions: Open surgical treatment volumes remained relatively stable over the study period, whereas the introduction of CCH was associated with increased overall treatment utilization and a reduction in the proportional share of surgical procedures. This shift coincided with substantial growth in public interest in nonsurgical therapies. Concurrent declines in inflation-adjusted reimbursement across all treatments highlight ongoing financial pressures on clinicians, particularly in the context of high-cost therapies such as CCH. Collectively, these findings underscore the importance of evidence-based, value-conscious decision making to ensure that treatment selection is driven by clinical effectiveness and cost-efficiency rather than external influences such as public interest or marketing. Clinical relevance: Treatment patterns for DC have evolved alongside the introduction of less invasive therapies and increasing public awareness. Understanding how utilization, reimbursement, and public interest intersect is essential for informed, evidence-based decision making in the management of DC.

Indexed as

Collagenase Clostridium histolyticumDupuytren contractureDupuytren diseaseNeedle fasciotomyXiaflex

Identifiers

PMID42621427
PMCPMC13487675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.