SynthesisFrontiers in psychiatry2026
Caregiver burden among caregivers of patients with depression: a systematic review and meta-analysis.
Synthesis in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Background: Depression is a highly prevalent mental disorder with a global distribution. Informal caregivers are integral to the long-term care of individuals with depression. However, they frequently experience substantial caregiver burden, detrimentally impacting both caregiver well-being and patient prognosis. Despite the clinical significance of this issue, there is currently no systematic review or meta-analysis quantifying the overall magnitude of this burden and synthesizing its associated factors among informal caregivers of patients with depression. Objective: This study aimed to assess the level of caregivers' burden among informal caregivers who are taking care of patients with depression and to systematically evaluate the associated factors through a narrative synthesis guided by the Stress-Appraisal Model. Methods: Eight electronic databases (PubMed, MEDLINE, Embase, PsycINFO, Web of Science, CNKI, Wan fang, and VIP) were systematically searched. Data extraction and quantitative synthesis were performed using STATA version 18.0. Statistical heterogeneity was assessed via Cochran's Q test and the Results: The current systematic review and meta-analysis comprised all 1366 research respondents from 11 studies. The overall pooled mean score of caregiver burden was 38.15 (95% CI: 31.38, 44.92; Conclusion: The current systematic review and meta-analysis showed that caregivers of patients with depression generally experience substantial caregiving burden, with pooled effect estimates indicating that the overall severity of this burden approaches the moderate level. Nevertheless, due to the limited quantity of caregiving burden is affected by multiple clinical variables. Accordingly, the findings of current systematic reviews should be interpreted with caution. Furthermore, this study proposes that public health interventions targeting mental health indicators and social support systems should be implemented for informal caregivers of individuals with depression, with the objectives of reducing the caregiving burden of this population and potentially improving the quality of care accessed by patients with depression. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD420261373459, identifier CRD420261373459.
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