Evidence map›Paper›PMID 42621223›Full record

ArticleComprehensive psychoneuroendocrinology2026

The oxytocinergic system in functional neurological disorder: Preliminary testing of associations with interoception and childhood trauma.

Natascha Stoffel, Juan Ansede-Bermejo, Cristina Concetti, Ángel Carracedo, Selma Aybek

Abstract read
In one paragraph

Article in Comprehensive psychoneuroendocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natascha StoffelFaculty of Science and Medicine, University of Fribourg, Switzerland.
Juan Ansede-BermejoFundación Pública Galega de Medicina Xenómica, Centro Nacional de Genotipado, Santiago de Compostela, Spain.
Cristina ConcettiFaculty of Science and Medicine, University of Fribourg, Switzerland.
Ángel CarracedoFundación Pública Galega de Medicina Xenómica, Centro Nacional de Genotipado, Santiago de Compostela, Spain.
Selma AybekFaculty of Science and Medicine, University of Fribourg, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oxytocinergic system has been proposed as a vulnerability factor in the pathophysiology of Functional Neurological Disorder (FND), a condition associated with stressful life-events and disturbed bodily awareness. Recent work from our group demonstrated reduced interoceptive function alongside elevated salivary oxytocin (OXT) levels in patients with mixed-FND. Here, we tested the same patients with FND (N = 41) and matched healthy controls (N = 48) of that study, addressing two additional aims: (I) exploratively testing the genetic associations of the oxytocin receptor gene (

Indexed as

Childhood traumaInteroceptionMethylationOXTRSalivary oxytocin

Identifiers

PMID42621223
PMCPMC13487256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.