Evidence map›Paper›PMID 42621152›Full record

ArticleiScience2026

A host-adapted commensal fungus from pet store mice drives type 2 immunity and cross-kingdom protection.

Geongoo Han, Rebecca Yunker, Mohammad H Hasan, Alex Bruce, Kellie Baldaro, Jessica Pacia, Nicholas N Jarjour, Lalit K Beura, Shipra Vaishnava

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Geongoo HanMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.
Rebecca YunkerMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.
Mohammad H HasanMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.
Alex BruceMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.
Kellie BaldaroMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.
Jessica PaciaMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.
Nicholas N JarjourCenter for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Lalit K BeuraMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.
Shipra VaishnavaMolecular Microbiology & Immunology Department, Brown University, Providence, RI 02912, USA.

Funding

The role of Sirtuins in neurodegenerative diseaseP20GM109035 · NIGMS · BROWN UNIVERSITY · PI RAND, DAVID M · 2016 to 2025
$22.6M
Vitamin A metabolism at the host-microbiome interfaceR01DK113265 · NIDDK · BROWN UNIVERSITY · PI Shipra Vaishnava · 2018 to 2026
$4.0M
SEM for serial block-face imagingS10OD023461 · OD · BROWN UNIVERSITY · PI CRETON, ROBBERT J · 2017 to 2017
$791k
Cytokine regulation of recirculating and tissue-resident memory CD8+ T cells in homeostasis and inflammationK22AI177360 · NIAID · VERSITI BLOOD HEALTH, INC. · PI Nicholas N Jarjour · 2025 to 2026
$203k
NIAID NIH HHS K22 AI177360NIDDK NIH HHS R01 DK113265NIGMS NIH HHS P20 GM109035NIH HHS S10 OD023461
6 · The paper itself

Abstract

To better mimic natural immunity, researchers utilize naturalized, wilded, wildling, and dirty/pet store mouse models with natural microbial exposure. This study screened the gut mycobiome of pet store mice and identified

Indexed as

commensal fungicross-kingdom protectionhost adaptationKazachstania pintolopesiimicrobiometype 2 immunity

Identifiers

PMID42621152
PMCPMC13486987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.