Evidence map›Paper›PMID 42621147›Full record

ArticleCureus2026

Comparative Evaluation of Automated Retreatment Systems for Bioceramic Sealer Removal: An In Vitro Scanning Electron Microscopic Study.

Sufia Parveen, Shalini Kumari, Chi Koy Wang, Abhinav Kumar Singh, Somnath Pal, Binoy Kumar Singh, Navin Mishra

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sufia ParveenDepartment of Conservative Dentistry and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, IND.
Shalini KumariDepartment of Conservative Dentistry and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, IND.
Chi Koy WangDepartment of Conservative Dentistry and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, IND.
Abhinav Kumar SinghDepartment of Conservative Dentistry and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, IND.
Somnath PalDepartment of Conservative Dentistry and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, IND.
Binoy Kumar SinghDepartment of Conservative Dentistry and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, IND.
Navin MishraDepartment of Conservative Dentistry and Endodontics, Post Graduate Institute of Dental Education and Research (PGIDER), Indira Gandhi Institute of Medical Sciences, Patna, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCalcium silicate-based bioceramic sealers have gained widespread acceptance because of their excellent sealing ability and biocompatibility. However, their strong adhesion to dentinal walls poses a significant challenge during nonsurgical endodontic retreatment. This study evaluated and compared the efficacy of the Neoendo Retreatment (Neoendo, Orikam Healthcare India Pvt. Ltd., Gurugram, India), ProTaper Universal Retreatment (Dentsply Sirona, Ballaigues, Switzerland), and HyFlex Remover (COLTENE/Whaledent AG, Altstätten, Switzerland) file systems in removing bioceramic sealers from root canal walls using scanning electron microscopy (SEM). MATERIALS AND

methodsThis in vitro study evaluated 45 extracted human mandibular premolars obturated with a calcium silicate-based bioceramic sealer and thermoplasticized gutta-percha. After standardized root canal preparation and obturation, the specimens were randomly allocated into three groups (n = 15) according to the retreatment system used: Neoendo Retreatment, ProTaper Universal Retreatment, and HyFlex Remover. Following retreatment, the roots were longitudinally sectioned and examined under scanning electron microscopy (SEM) at ×1000 magnification. The presence of residual bioceramic sealer in the coronal, middle, and apical thirds was assessed using the modified Ezzie scoring system. Data were analyzed using the Friedman and Kruskal-Wallis tests, followed by Dunn's multiple comparisons test, where appropriate, with statistical significance set at p < 0.05.

resultsAll three retreatment systems left residual bioceramic sealer on the canal walls, and none achieved complete removal. Within each retreatment system, residual bioceramic sealer scores differed significantly among the coronal, middle, and apical thirds (Friedman test, p < 0.05). Dunn's post hoc analysis demonstrated significantly higher residual sealer scores in the apical third than in the coronal third, whereas no significant differences were observed between the coronal and middle thirds or between the middle and apical thirds. Intergroup comparisons revealed no statistically significant differences among the Neoendo Retreatment, ProTaper Universal Retreatment, and HyFlex Remover systems at any root canal level (p > 0.05), although the HyFlex Remover system showed a trend toward lower residual sealer scores. SEM analysis demonstrated region-specific differences in canal cleanliness, characterized by cleaner dentinal surfaces in the coronal third and greater residual bioceramic sealer with marked dentinal tubule occlusion in the apical third.

conclusionNeoendo Retreatment, ProTaper Universal Retreatment, and HyFlex Remover exhibited comparable efficacy in bioceramic sealer removal. Complete sealer removal remains unattainable, particularly in the apical third, highlighting the need for adjunctive cleaning strategies to improve the retreatment outcomes.

Indexed as

bioceramic sealerendodontic retreatmenthyflex removerneoendo retreatmentprotaper universal retreatmentroot canal sealerscanning electron microscopy

Identifiers

PMID42621147
PMCPMC13486631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.