Evidence map›Paper›PMID 42621121›Full record

ArticleiScience2026

Integration of the circulating miRNome and clinical information to predict 90-day mortality in elderly COVID-19 subphenotypes.

Manel Perez-Pons, Iván D Benítez, Marta Molinero, María C García-Hidalgo, Carlos Rodríguez-Muñoz, Miguel Sanchez-Rodriguez, Thalía Belmonte, Marina Rogel Vilanova, Pilar Nogales Moreno, Mariona Puente Moreno and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Manel Perez-PonsClinical and Molecular Phenotyping, Biomedical Research Institute of Lleida - Dr. Pifarré Foundation, IRBLleida, Lleida, Spain.
Iván D BenítezCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Marta MolineroClinical and Molecular Phenotyping, Biomedical Research Institute of Lleida - Dr. Pifarré Foundation, IRBLleida, Lleida, Spain.
María C García-HidalgoClinical and Molecular Phenotyping, Biomedical Research Institute of Lleida - Dr. Pifarré Foundation, IRBLleida, Lleida, Spain.
Carlos Rodríguez-MuñozClinical and Molecular Phenotyping, Biomedical Research Institute of Lleida - Dr. Pifarré Foundation, IRBLleida, Lleida, Spain.
Miguel Sanchez-RodriguezClinical and Molecular Phenotyping, Biomedical Research Institute of Lleida - Dr. Pifarré Foundation, IRBLleida, Lleida, Spain.
Thalía BelmonteClinical and Molecular Phenotyping, Biomedical Research Institute of Lleida - Dr. Pifarré Foundation, IRBLleida, Lleida, Spain.
Marina Rogel VilanovaHospital Universitario Arnau de Vilanova, Lleida, Spain.
Pilar Nogales MorenoHospital Universitario Arnau de Vilanova, Lleida, Spain.
Mariona Puente MorenoHospital Universitario Arnau de Vilanova, Lleida, Spain.
Elena Balaña PrimHospital Universitario Arnau de Vilanova, Lleida, Spain.
Thais ComellaHospital Universitario Santa María, Lleida, Spain.
Anna Pérez-SainzHospital Universitario Santa María, Lleida, Spain.
Irene CuadratHospital Universitario Santa María, Lleida, Spain.
Laia Utrillo-MontagutHospital Universitario Santa María, Lleida, Spain.
Francisco Nicolas-SánchezHospital Universitario Santa María, Lleida, Spain.
Anna Moncusí-MoixCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Clara Gort-PanielloCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Tamara PostigoCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Alicia OrtegaGroup for Biomedical Research in Sepsis (BioSepsis), Instituto de Investigación Biomédica de Salamanca (IBSAL), Gerencia Regional de Salud de Castilla y León, Paseo de San Vicente, Salamanca, Spain.
Jessica GonzálezCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Ferran BarbéCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Jesús F Bermejo-MartinCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
Gerard TorresCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.
David de Gonzalo-CalvoClinical and Molecular Phenotyping, Biomedical Research Institute of Lleida - Dr. Pifarré Foundation, IRBLleida, Lleida, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elderly patients with coronavirus disease 2019 (COVID-19) exhibit high mortality rates. We assessed whether microRNA (miRNA) profiling provides prognostic information in this population. This multicenter study included hospitalized COVID-19 patients aged ≥65 years (

Indexed as

biomarkerscluster analysiselderly COVID-19 patientsmachine learningmiRNAsmortality prognostic modelssubphenotypes

Identifiers

PMID42621121
PMCPMC13486767

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.