Evidence map›Paper›PMID 42621066›Full record

ArticleFrontiers in digital health2026

Digital and traditional recruitment strategies and participation patterns in the multicenter Healthy Brain Ageing study.

Daniel F Pilco-Janeta, Philipp Mahlknecht, Myriam De la Cruz-Puebla, Corinne Horlings, Alicia Garrido, Taina M Marques, Ruxandra Soare, Christoph Theyer, Simon Leiter, Soumyabrata Ghosh and 13 more

Abstract read
In one paragraph

Article in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Daniel F Pilco-JanetaParkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.
Philipp MahlknechtDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Myriam De la Cruz-PueblaParkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.
Corinne HorlingsDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Alicia GarridoParkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.
Taina M MarquesTransversal Translational Medicine, Luxembourg Institute of Health, Strassen, Luxembourg.
Ruxandra SoareLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Christoph TheyerDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Simon LeiterDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Soumyabrata GhoshLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Kavita RegeLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Iris EgnerDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Jón Pol GalesTransversal Translational Medicine, Luxembourg Institute of Health, Strassen, Luxembourg.
Sebastian SchadeParacelsus-Elena-Klinik Kassel, Kassel, Germany.
Andrés GranollesDigital Marketing Agency, Altoclick, Barcelona, Spain.
Fernanda FarfanParkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.
Venkata P SatagopamLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Claudia TrenkwalderParacelsus-Elena-Klinik Kassel, Kassel, Germany.
Brit MollenhauerParacelsus-Elena-Klinik Kassel, Kassel, Germany.
Rejko KrügerLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Werner PoeweDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Eduardo TolosaParkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.
María-José MartíParkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early detection of Parkinson's disease (PD) benefits from innovative approaches such as large-scale online surveys on different risk factors in the general population. Effective dissemination is essential, yet little is known about the relative reach and recruitment patterns of different strategies. Objective: To describe dissemination strategies used in the multicenter Healthy Brain Ageing (HeBA) study and characterize center-specific recruitment-source, web-access, demographic, and survey-completion patterns across three European centers. Methods: Data from three centers (Barcelona, Spain; Luxembourg, Luxembourg; and Innsbruck, Austria) aiming at remotely identifying PD risk factors and prodromal symptoms were analyzed. Dissemination strategies were categorized as digital or traditional. Descriptive statistics summarized dissemination strategies, geographic web-access patterns, linguistic adaptation, recruitment sources, and survey completion. Results: At the campaign level, digital dissemination predominated in Barcelona (55.7%) and Luxembourg (53.3%), whereas Innsbruck used a slightly higher proportion of traditional campaigns (52.2%). Participant-reported recruitment sources showed center-specific patterns: digital advertising was the most frequent reported source in Barcelona (62.5%), flyers or invitation letters in Luxembourg (39.3%), and radio or television in Innsbruck (31.4%). Sex-based recruitment differences were significant in Luxembourg ( Conclusions: Recruitment-related patterns differed across centers and reflected locally implemented combinations of digital and traditional dissemination channels. These findings suggest that recruitment strategies for large-scale online health studies may benefit from considering local media ecosystems, language contexts, and digital participation patterns.

Indexed as

dissemination strategieshealth communicationonline health surveyParkinson's diseaseparticipant recruitment strategies

Identifiers

PMID42621066
PMCPMC13486224

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.